CD38 (SP149) on bone marrow.
CD38 (SP149) Rabbit Monoclonal Antibody
Specialties: Hematopathology
Updated: 2022-09-09 14:49:06
CD38 molecule is a 46-kDa type-II transmembrane glycoprotein with a short N-terminal cytoplasmic tail (20 amino acids) and a long extracellular domain (256 amino acids). It is present on many hematopoietic cells, especially plasma cells, and in some solid tumor tissues.1-3 CD38 is one of the early expressed markers of mature naive B-cell activation and it is useful in identifying functional mature B-lymphocyte subsets.1-3
- Martin, Flavius, and John F Kearney. "Marginal-zone B cells." Nature reviews. Immunology vol. 2,5 (2002): 323-35.
- Dono, M et al. "Heterogeneity of tonsillar subepithelial B lymphocytes, the splenic marginal zone equivalents." Journal of immunology (Baltimore, Md. : 1950) vol. 164,11 (2000): 5596-604.
- Malavasi, Fabio et al. "Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology." Physiological reviews vol. 88,3 (2008): 841-86.
Specifications
- Reactivity: paraffin
- Control: Plasma cell myeloma (Cytoplasmic, Membranous); Plasma Cells (Cytoplasmic, Membranous); Lymph node (Cytoplasmic, Membranous); Bone Marrow (Cytoplasmic, Membranous)
- Dilution Range: 1:100-1:500 *
Package Inserts
IFU
- IVD Rev. 3.0 (CMC11831030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 118R-14 |
| 0.5 mL concentrate | 118R-15 |
| 1.0 mL concentrate | 118R-16 |
| 1.0 mL predilute ready-to-use | 118R-17 |
| 7.0 mL predilute ready-to-use | 118R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 118R-14 |
| 0.5 mL concentrate | 118R-15 |
| 1.0 mL concentrate | 118R-16 |
| 1.0 mL predilute ready-to-use | 118R-17 |
| 7.0 mL predilute ready-to-use | 118R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 118R-14 |
| 0.5 mL concentrate | 118R-15 |
| 1.0 mL concentrate | 118R-16 |
| 1.0 mL predilute ready-to-use | 118R-17 |
| 7.0 mL predilute ready-to-use | 118R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 118R-14-RUO |
| 0.5 mL concentrate (RUO) | 118R-15-RUO |
| 1.0 mL concentrate (RUO) | 118R-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 118R-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 118R-18-RUO |
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