CD138/syndecan-1 (B-A38) Mouse Monoclonal Antibody
Specialties: Hematopathology
CD138, Syndecan 1, is a transmembrane heparan sulfate proteoglycan, present mainly in a variety of epithelial tissues, participating in cell proliferation, cell migration, intercellular communication and cell-matrix interactions.1 In lymphoid tissues, CD138 is expressed in the late stages of B-cell differentiation with progression towards plasma cells.1,2 Anti-CD138 is a good marker to selectively identify plasma cells, benign or malignant, in lymphoid tissues3,4 CD138 is also expressed in a variety of epithelial cells.4
- Chilosi M, et al. CD138/syndecan-1: a useful immunohistochemical marker of normal and neoplastic plasma cells on routine trephine bone marrow biopsies. Mod Pathol. 1999; 12:1101-6.
- Sebestyén A, et al. Syndecan-1 (CD138) expression in human non-Hodgkin lymphomas. Br J Haematol. 1999; 104:412-9.
- Bayer-Garner IB, et al. Syndecan-1 (CD138) immunoreactivity in bone marrow biopsies of multiple myeloma: shed syndecan-1 accumulates in fibrotic regions. Mod Pathol. 2001; 14:1052-8.
- O'Connell FP, et al. CD138 (syndecan-1), a plasma cell marker immunohistochemical profile in hematopoietic and nonhematopoietic neoplasms. Am J Clin Pathol. 2004; 121:254-63.
Specifications
- Reactivity: paraffin
- Control: Tonsil (Membranous)
- Dilution Range: 1:25-1:200 *
Package Inserts
IFU
- IVD Rev. 6.0 (CMC13821060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 25.0 mL predilute ready-to-use | 138M-10 |
| 0.1 mL concentrate | 138M-14 |
| 0.5 mL concentrate | 138M-15 |
| 1.0 mL concentrate | 138M-16 |
| 1.0 mL predilute ready-to-use | 138M-17 |
| 7.0 mL predilute ready-to-use | 138M-18 |
For in vitro diagnostic (IVD) use in Canada
| 25.0 mL predilute ready-to-use | 138M-10 |
| 0.1 mL concentrate | 138M-14 |
| 0.5 mL concentrate | 138M-15 |
| 1.0 mL concentrate | 138M-16 |
| 1.0 mL predilute ready-to-use | 138M-17 |
| 7.0 mL predilute ready-to-use | 138M-18 |
For in vitro diagnostic (IVD) use in Europe
| 25.0 mL predilute ready-to-use | 138M-10 |
| 0.1 mL concentrate | 138M-14 |
| 0.5 mL concentrate | 138M-15 |
| 1.0 mL concentrate | 138M-16 |
| 1.0 mL predilute ready-to-use | 138M-17 |
| 7.0 mL predilute ready-to-use | 138M-18 |
For research use only (RUO) in Japan
| 25.0 mL predilute ready-to-use (RUO) | 138M-10-RUO |
| 0.1 mL concentrate (RUO) | 138M-14-RUO |
| 0.5 mL concentrate (RUO) | 138M-15-RUO |
| 1.0 mL concentrate (RUO) | 138M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 138M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 138M-18-RUO |
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