FoxP1 (SP133) Rabbit Monoclonal Antibody
Specialties: Hematopathology
Forkhead box P1 (FOXP1) is a transcription factor normally expressed in many cellular processes and plays an important role in development, specifically in human leukocyte populations.1,2 Expression of FOXP1 can be found in neoplastic and non-neoplastic tissues.2 Overexpression of FOXP1 has been observed in a subset of diffuse large B-cell lymphoma (DLBCL), and thus FOXP1 immunohistochemistry has been shown to be helpful in the subclassification of DLBCL.2
- Garaud S, et al. FOXP1 is a regulator of quiescence in healthy human CD4+ T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders. Eur. J. Immunol. 2017; 47:168-79.
- Wlodarska I, et al. FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations. Leukemia. 2005; 19:1299-305.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: tonsil, lymph node
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 3.0 (CMC35031030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
0.1 mL concentrate | 350R-14 |
0.5 mL concentrate | 350R-15 |
1 mL concentrate | 350R-16 |
1 mL predilute | 350R-17 |
7 mL predilute | 350R-18 |
For in vitro diagnostic (IVD) use in Canada
0.1 mL concentrate | 350R-14 |
0.5 mL concentrate | 350R-15 |
1 mL concentrate | 350R-16 |
1 mL predilute | 350R-17 |
7 mL predilute | 350R-18 |
For in vitro diagnostic (IVD) use in Europe
0.1 mL concentrate | 350R-14 |
0.5 mL concentrate | 350R-15 |
1 mL concentrate | 350R-16 |
1 mL predilute | 350R-17 |
7 mL predilute | 350R-18 |
For research use only (RUO) in Japan
0.1 mL concentrate | 350R-14-RUO |
0.5 mL concentrate | 350R-15-RUO |
1 mL concentrate | 350R-16-RUO |
1 mL predilute | 350R-17-RUO |
7 mL predilute | 350R-18-RUO |
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