Germinal center cells demonstrate strong cytoplasmic CD10 protein expression.
CD10 (56C6) Mouse Monoclonal Antibody
Specialties: Hematopathology
Updated: 2023-12-01 15:29:05
CD10, common acute lymphoblastic leukemia antigen, is expressed by a subset of T follicular helper cells.1,2 CD10 has a direct role in cell growth and apoptosis and has been implicated in tumor cells proliferation.3 CD10 expression has been reported in a variety of tissues; including renal cell carcinoma, hepatocellular carcinoma, and follicular lymphoma.4, 5
- Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96.
- Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
- Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
- Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
- Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.
Specifications
- Reactivity: paraffin
- Control: Kidney (Cytoplasmic, Membranous); Lymph node (Cytoplasmic, Membranous); Tonsil (Cytoplasmic, Membranous)
- Dilution Range: 1:10-1:50 *
Package Inserts
IFU
- IVD Rev. 7.0 (CMC11021070)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 25.0 mL predilute ready-to-use | 110M-10 |
| 0.1 mL concentrate | 110M-14 |
| 0.5 mL concentrate | 110M-15 |
| 1.0 mL concentrate | 110M-16 |
| 1.0 mL predilute ready-to-use | 110M-17 |
| 7.0 mL predilute ready-to-use | 110M-18 |
For in vitro diagnostic (IVD) use in Canada
| 25.0 mL predilute ready-to-use | 110M-10 |
| 0.1 mL concentrate | 110M-14 |
| 0.5 mL concentrate | 110M-15 |
| 1.0 mL concentrate | 110M-16 |
| 1.0 mL predilute ready-to-use | 110M-17 |
| 7.0 mL predilute ready-to-use | 110M-18 |
For in vitro diagnostic (IVD) use in Europe
| 25.0 mL predilute ready-to-use | 110M-10 |
| 0.1 mL concentrate | 110M-14 |
| 0.5 mL concentrate | 110M-15 |
| 1.0 mL concentrate | 110M-16 |
| 1.0 mL predilute ready-to-use | 110M-17 |
| 7.0 mL predilute ready-to-use | 110M-18 |
For research use only (RUO) in Japan
| 25.0 mL predilute ready-to-use (RUO) | 110M-10-RUO |
| 0.1 mL concentrate (RUO) | 110M-14-RUO |
| 0.5 mL concentrate (RUO) | 110M-15-RUO |
| 1.0 mL concentrate (RUO) | 110M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 110M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 110M-18-RUO |
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