Nuclear labelling of mantle cell lymphoma by SOX-11 antibody.
SOX-11 (MRQ-58) Mouse Monoclonal Antibody
Specialties: Hematopathology
Updated: 2022-07-05 10:31:30
SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination.1,3 Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).2,3
- Hargrave, M et al. Expression of the SOX-11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Dev Dyn 1997; 210:79-86.
- Zeng W, et al. Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX-11 expression. Am J Surg Pathol 2012; 36:214-9.
- Narurkar R, et al. SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma. Biomark Res. 2016; 4:6.
Specifications
- Reactivity: paraffin
- Control: Mantle cell lymphoma (Nuclear)
- Dilution Range: 1:25-1:100 *
Package Inserts
IFU
- IVD Rev. 4.0 (CMC38221040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 25.0 mL predilute ready-to-use | 382M-10 |
| 0.1 mL concentrate | 382M-14 |
| 0.5 mL concentrate | 382M-15 |
| 1.0 mL concentrate | 382M-16 |
| 1.0 mL predilute ready-to-use | 382M-17 |
| 7.0 mL predilute ready-to-use | 382M-18 |
For in vitro diagnostic (IVD) use in Canada
| 25.0 mL predilute ready-to-use | 382M-10 |
| 0.1 mL concentrate | 382M-14 |
| 0.5 mL concentrate | 382M-15 |
| 1.0 mL concentrate | 382M-16 |
| 1.0 mL predilute ready-to-use | 382M-17 |
| 7.0 mL predilute ready-to-use | 382M-18 |
For in vitro diagnostic (IVD) use in Europe
| 25.0 mL predilute ready-to-use | 382M-10 |
| 0.1 mL concentrate | 382M-14 |
| 0.5 mL concentrate | 382M-15 |
| 1.0 mL concentrate | 382M-16 |
| 1.0 mL predilute ready-to-use | 382M-17 |
| 7.0 mL predilute ready-to-use | 382M-18 |
For research use only (RUO) in Japan
| 25.0 mL predilute ready-to-use (RUO) | 382M-10-RUO |
| 0.1 mL concentrate (RUO) | 382M-14-RUO |
| 0.5 mL concentrate (RUO) | 382M-15-RUO |
| 1.0 mL concentrate (RUO) | 382M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 382M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 382M-18-RUO |
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