Case Study #3

April 2017


A 62 year old HIV-negative male non-smoker and non-drinker has chronic fever, fatigue, and weight loss over a 30 day period. His WBC was 9500 with 81% lymphocytes, his hemoglobin was 12.4 and his LDH was 370. Physical examination shows swelling in the neck and abdomen, and a CT scan shows signs of splenomegaly and central and peripheral lymphadenopathy, with progressively enlarging retroperitoneal lymph nodes. A lymph node biopsy was taken and the histology stains are below.
What is the diagnosis?