Cell Marque Portfolio

CD10 (56C6)

Mouse Monoclonal


CD10, common acute lymphoblastic leukemia antigen, is expressed by a subset of T follicular helper cells.1,2 CD10 has a direct role in cell growth and apoptosis and has been implicated in tumor cells proliferation.3 CD10 expression has been reported in a variety of tissues; including renal cell carcinoma, hepatocellular carcinoma, and follicular lymphoma.4, 5

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: kidney, lymph node, tonsil,
  • Isotype: IgG1
  • Dilution Range: 1:10-1:50*

Protocols


  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C + AMP

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Keycode Specific IFU

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*Note: IFUs with the prefix RUO or ASR are only available for download in English.


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References


  1. Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96.
  2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
  3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
  4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
  5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.

Literature

Last updated: 2017-04-25 15:36:56

CD10
Germinal center cells demonstrate strong cytoplasmic CD10 protein expression.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: kidney, lymph node, tonsil,
  • Isotype: IgG1
  • Dilution Range: 1:10-1:50*

Protocols


  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C + AMP

References


  1. Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96.
  2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
  3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
  4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
  5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.

Download an IFU

Select revision:


Download SDS


Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 110M-14
0.5 ml, concentrate 110M-15
1 ml, concentrate 110M-16
1 ml, predilute 110M-17
7 ml, predilute 110M-18
25 ml, predilute 110M-10

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 110M-14
0.5 ml, concentrate 110M-15
1 ml, concentrate 110M-16
1 ml, predilute 110M-17
7 ml, predilute 110M-18
25 ml, predilute 110M-10

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 110M-14
0.5 ml, concentrate 110M-15
1 ml, concentrate 110M-16
1 ml, predilute 110M-17
7 ml, predilute 110M-18
25 ml, predilute 110M-10

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 110M-14-RUO
0.5 ml, concentrate 110M-15-RUO
1 ml, concentrate 110M-16-RUO
1 ml, predilute 110M-17-RUO
7 ml, predilute 110M-18-RUO
25 ml, predilute 110M-10-RUO

Literature

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: kidney, lymph node, tonsil,
  • Isotype: IgG1
  • Dilution Range: 1:10-1:50*

Protocols


  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C + AMP

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

Download SDS

References


  1. Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96.
  2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
  3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
  4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
  5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.
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