CD10 (56C6) Mouse Monoclonal Antibody

CD10
Germinal center cells demonstrate strong cytoplasmic CD10 protein expression.

CD10 (56C6) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD10, common acute lymphoblastic leukemia antigen, is expressed by a subset of T follicular helper cells.1,2 CD10 has a direct role in cell growth and apoptosis and has been implicated in tumor cells proliferation.3 CD10 expression has been reported in a variety of tissues; including renal cell carcinoma, hepatocellular carcinoma, and follicular lymphoma.4, 5

  1. Maguer-Satta V, et al. Concise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer. Stem Cells. 2011; 29:389-96.
  2. Laurent C, et al. A novel subset of T-helper cells: follicular T-helper cells and their markers. Haematologica. 2010; 95: 356-8.
  3. Onak NK, et al. CD10 expression in urothelial bladder carcinomas: staining patterns and relationship with pathologic parameters. Turk J Med Sci. 2010; 40:177-84.
  4. Chu P, et al. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Am J Clin Pathol. 2000; 113: 374-82.
  5. Swerdlow S, et al. WHO classification of tumours of hematopoietic and lymphoid tissues. 4th edition. 2008. P. 220,233,255,265,309.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: kidney, lymph node, tonsil,
  • Dilution Range: 1:10-1:50*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

25 mL predilute110M-10
0.1 mL concentrate110M-14
0.5 mL concentrate110M-15
1 mL concentrate110M-16
1 mL predilute110M-17
7 mL predilute110M-18

For in vitro diagnostic (IVD) use in Canada

25 mL predilute110M-10
0.1 mL concentrate110M-14
0.5 mL concentrate110M-15
1 mL concentrate110M-16
1 mL predilute110M-17
7 mL predilute110M-18

For in vitro diagnostic (IVD) use in Europe

25 mL predilute110M-10
0.1 mL concentrate110M-14
0.5 mL concentrate110M-15
1 mL concentrate110M-16
1 mL predilute110M-17
7 mL predilute110M-18

For research use only (RUO) in Japan

25 mL predilute110M-10-RUO
0.1 mL concentrate110M-14-RUO
0.5 mL concentrate110M-15-RUO
1 mL concentrate110M-16-RUO
1 mL predilute110M-17-RUO
7 mL predilute110M-18-RUO

 

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