Cyclin D1 (SP4) Rabbit Monoclonal Antibody

Cyclin D1
Cyclin D1 (SP4) on lymph node.

Cyclin D1 (SP4) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

Cyclins are proteins that govern transitions through distinct phases of the cell cycle by regulating the activity of the cyclin-dependent kinases.1 Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene found in a wide variety of human neoplasms. This antibody is useful for distinguishing mantle cell lymphomas (cyclin D1 positive).2

  1. Bartkova J, et al. Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer. Cancer Research. 1995; 55:949-56.
  2. Hankin RC, et al. Mantle cell lymphoma. Arch Pathol Lab Med. 1999; 123:1182-8.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: mantle cell lymphoma
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate241R-14
0.5 mL concentrate241R-15
1 mL concentrate241R-16
1 mL predilute241R-17
7 mL predilute241R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate241R-14
0.5 mL concentrate241R-15
1 mL concentrate241R-16
1 mL predilute241R-17
7 mL predilute241R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate241R-14
0.5 mL concentrate241R-15
1 mL concentrate241R-16
1 mL predilute241R-17
7 mL predilute241R-18

For research use only (RUO) in Japan

0.1 mL concentrate241R-14-RUO
0.5 mL concentrate241R-15-RUO
1 mL concentrate241R-16-RUO
1 mL predilute241R-17-RUO
7 mL predilute241R-18-RUO

 

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