Cyclin D1 (SP4) on lymph node.
Cyclin D1 (SP4) Rabbit Monoclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
Cyclins are proteins that govern transitions through distinct phases of the cell cycle by regulating the activity of the cyclin-dependent kinases.1 Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene found in a wide variety of human neoplasms. This antibody is useful for distinguishing mantle cell lymphomas (cyclin D1 positive).2
- Bartkova J, et al. Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer. Cancer Research. 1995; 55:949-56.
- Hankin RC, et al. Mantle cell lymphoma. Arch Pathol Lab Med. 1999; 123:1182-8.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: mantle cell lymphoma
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC24131040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 241R-14 |
| 0.5 mL concentrate | 241R-15 |
| 1 mL concentrate | 241R-16 |
| 1 mL predilute | 241R-17 |
| 7 mL predilute | 241R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 241R-14 |
| 0.5 mL concentrate | 241R-15 |
| 1 mL concentrate | 241R-16 |
| 1 mL predilute | 241R-17 |
| 7 mL predilute | 241R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 241R-14 |
| 0.5 mL concentrate | 241R-15 |
| 1 mL concentrate | 241R-16 |
| 1 mL predilute | 241R-17 |
| 7 mL predilute | 241R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 241R-14-RUO |
| 0.5 mL concentrate | 241R-15-RUO |
| 1 mL concentrate | 241R-16-RUO |
| 1 mL predilute | 241R-17-RUO |
| 7 mL predilute | 241R-18-RUO |
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