Cell Marque Portfolio

SOX-11 (MRQ-58)

Mouse Monoclonal


SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination.1,3 Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).2,3

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: mantle cell lymphoma
  • Isotype: IgG1
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER2/20

References


  1. Hargrave, M et al. Expression of the SOX-11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Dev Dyn 1997; 210:79-86.
  2. Zeng W, et al. Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX-11 expression. Am J Surg Pathol 2012; 36:214-9.
  3. Narurkar R, et al. SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma. Biomark Res. 2016; 4:6.

Last updated: 2017-05-24 08:46:09

SOX-11
Nuclear labelling of mantle cell lymphoma by SOX-11 antibody.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: mantle cell lymphoma
  • Isotype: IgG1
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER2/20

References


  1. Hargrave, M et al. Expression of the SOX-11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Dev Dyn 1997; 210:79-86.
  2. Zeng W, et al. Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX-11 expression. Am J Surg Pathol 2012; 36:214-9.
  3. Narurkar R, et al. SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma. Biomark Res. 2016; 4:6.

Package Inserts

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Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 mL concentrate 382M-14
0.5 mL concentrate 382M-15
1 mL concentrate 382M-16
1 mL predilute 382M-17
7 mL predilute 382M-18
25 mL predilute 382M-10

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 mL concentrate 382M-14
0.5 mL concentrate 382M-15
1 mL concentrate 382M-16
1 mL predilute 382M-17
7 mL predilute 382M-18
25 mL predilute 382M-10

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 mL concentrate 382M-14
0.5 mL concentrate 382M-15
1 mL concentrate 382M-16
1 mL predilute 382M-17
7 mL predilute 382M-18
25 mL predilute 382M-10

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 mL concentrate 382M-14-RUO
0.5 mL concentrate 382M-15-RUO
1 mL concentrate 382M-16-RUO
1 mL predilute 382M-17-RUO
7 mL predilute 382M-18-RUO
25 mL predilute 382M-10-RUO

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: mantle cell lymphoma
  • Isotype: IgG1
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER2/20

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References


  1. Hargrave, M et al. Expression of the SOX-11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Dev Dyn 1997; 210:79-86.
  2. Zeng W, et al. Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX-11 expression. Am J Surg Pathol 2012; 36:214-9.
  3. Narurkar R, et al. SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma. Biomark Res. 2016; 4:6.
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