FSH (EP257) Rabbit Monoclonal Antibody
Specialties: Anatomic Pathology Neuropathology
Follicle-stimulating hormone (FSH) is a member of the pituitary glycoprotein hormone family which also includes luteinizing hormone (LH), chorionic gonadotropin (hCG), and thyroid-stimulating hormone (TSH).1 Members of the pituitary glycoprotein hormone family consist of a shared alpha chain and a beta chain encoded by a separate gene.1-3 The FSHB gene encodes the beta subunit of follicle stimulating hormone.1-3 FSH enables ovarian folliculogenesis and is essential for Sertoli cell proliferation and spermatogenesis.2 Anti-FSH is a useful marker in classification of pituitary neoplasms because it labels FSH-producing cells (gonadotrophs).3-5
- Baenziger JU, et al. Pituitary glycoprotein hormone oligosaccharides: Structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin. Biochim Biophys Acta. 1988; 947:287-306.
- Nussey SS, et al. Endocrinology: An integrated approach. BIOS Scientific Publishers Ltd; 2001 p. 217-79.
- Uccella S, et al. Localization of inhibin/activin subunits in normal pituitary and in pituitary adenomas. Pituitary. 2000; 3:131-9.
- Schmid M, et al. Pituitary hormone mRNA in null cell adenomas and oncocytomas by in situ hybridization comparison with immunohistochemical and clinical data. Pathol Res Pract. 2001; 197:663-9.
- La Rosa S, et al. Detection of gonadotropin-releasing hormone receptor in normal human pituitary cells and pituitary adenomas using immunohistochemistry. Virchows Arch. 2000; 437:264-9.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: pituitary
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC20731020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 207R-14 |
| 0.5 mL concentrate | 207R-15 |
| 1 mL concentrate | 207R-16 |
| 1 mL predilute | 207R-17 |
| 7 mL predilute | 207R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 207R-14 |
| 0.5 mL concentrate | 207R-15 |
| 1 mL concentrate | 207R-16 |
| 1 mL predilute | 207R-17 |
| 7 mL predilute | 207R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 207R-14 |
| 0.5 mL concentrate | 207R-15 |
| 1 mL concentrate | 207R-16 |
| 1 mL predilute | 207R-17 |
| 7 mL predilute | 207R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 207R-14-RUO |
| 0.5 mL concentrate | 207R-15-RUO |
| 1 mL concentrate | 207R-16-RUO |
| 1 mL predilute | 207R-17-RUO |
| 7 mL predilute | 207R-18-RUO |
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