TSH Rabbit Polyclonal Antibody
Specialties: Anatomic Pathology Neuropathology
Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrops in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits which are non-covalently bound to one another. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors.1-5
- Batanero E, et al. The neural and neuro-endocrine component of the human thymus. II. Hormone immunoreactivity. Brain Behav Immun. 1992; 6:249-64.
- Sanno N, et al. GH and PRL gene expression by nonradioisotopic in situ hybridization in TSH-secreting pituitary adenomas. J Clin Endocrinol Metab. 1995; 80:2518-22.
- La Rosa S, et al. Detection of gonadotropin-releasing hormone receptor in normal human pituitary cells and pituitary adenomas using immunohistochemistry. Virchows Arch. 2000; 437:264-9.
- Kuzuya N, et al. Endocrine and immunohistochemical studies on thyrotropin (TSH)-secreting pituitary adenomas: responses of TSH, alpha-subunit, and growth hormone to hypothalamic releasing hormones and their distribution in adenoma cells. J Clin Endocrinol Metab. 1990; 71:1103-11.
- Clore JN, et al. Thyrotropin-induced hyperthyroidism: evidence for a common progenitor stem cell. Am J Med Sci. 1988; 295:3-5.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: pituitary
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC21111040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 211A-14 |
| 0.5 mL concentrate | 211A-15 |
| 1 mL concentrate | 211A-16 |
| 1 mL predilute | 211A-17 |
| 7 mL predilute | 211A-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 211A-14 |
| 0.5 mL concentrate | 211A-15 |
| 1 mL concentrate | 211A-16 |
| 1 mL predilute | 211A-17 |
| 7 mL predilute | 211A-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 211A-14 |
| 0.5 mL concentrate | 211A-15 |
| 1 mL concentrate | 211A-16 |
| 1 mL predilute | 211A-17 |
| 7 mL predilute | 211A-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 211A-14-RUO |
| 0.5 mL concentrate | 211A-15-RUO |
| 1 mL concentrate | 211A-16-RUO |
| 1 mL predilute | 211A-17-RUO |
| 7 mL predilute | 211A-18-RUO |
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