Thyrocytes are labelled by anti-thyroglobulin.
Thyroglobulin (2H11+6E1) Mouse Monoclonal Antibody
Specialties: Head/Neck Pathology
Updated: 2022-10-13 12:51:31
Thyroglobulin (Tg) is the precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).1 Tg is a high molecular weight glycoprotein found in normal thyroid follicular cells.1,2 Thyroglobulin is useful for identifying thyroid origin of carcinoma of papillary and follicular types in the setting of carcinoma of unknown primary.2-5
- Sellitti DF and Suzuki K. Intrinsic regulation of thyroid function by thyroglobulin. Thyroid. 2014; 24:625-38.
- Bellet D, et al. Production and in vitro utilization of monoclonal antibodies to human thyroglobulin. J Clin Endocrinol Metab 1983; 56:530-3.
- Bejarano PA, et al. Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms. Appl Immunohistochem Mol Morphol. 2000; 8:189-94.
- Judkins AR, et al. Utility of immunohistochemistry in the evaluation of necrotic thyroid tumors. Hum Pathol. 1999; 30:1373-6.
- Hammar SP. Metastatic adenocarcinoma of unknown primary origin. Hum Pathol. 1998; 29:1393-1402.
Specifications
- Reactivity: paraffin
- Control: Thyroid (Cytoplasmic)
- Dilution Range: 1:100-1:500 *
Package Inserts
IFU
- IVD Rev. 5.0 (CMC34021050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 340M-14 |
| 0.5 mL concentrate | 340M-15 |
| 1.0 mL concentrate | 340M-16 |
| 1.0 mL predilute ready-to-use | 340M-17 |
| 7.0 mL predilute ready-to-use | 340M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 340M-14 |
| 0.5 mL concentrate | 340M-15 |
| 1.0 mL concentrate | 340M-16 |
| 1.0 mL predilute ready-to-use | 340M-17 |
| 7.0 mL predilute ready-to-use | 340M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 340M-14 |
| 0.5 mL concentrate | 340M-15 |
| 1.0 mL concentrate | 340M-16 |
| 1.0 mL predilute ready-to-use | 340M-17 |
| 7.0 mL predilute ready-to-use | 340M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 340M-14-RUO |
| 0.5 mL concentrate (RUO) | 340M-15-RUO |
| 1.0 mL concentrate (RUO) | 340M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 340M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 340M-18-RUO |
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