Rabbit monoclonal calcitonin antibody labels C-cells in this normal-appearing thyroid.
Calcitonin (SP17) Rabbit Monoclonal Antibody
Specialties: Cytopathology Head/Neck Pathology
Updated: 2018-01-11 08:35:53
Immunohistochemical staining with anti-calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities.1-5
- Copp DH, et al. Evidence for calcitonin--a new hormone from the parathyroid that lowers blood calcium. Endocrinology. 1962; 70:638-49.
- Kameda Y, et al. Development and cytodifferentiation of C cell complexes in dog fetal thyroids. An immunohistochemical study using anti-calcitonin, anti-C-thyroglobulin and anti-19S thyroglobulin antisera. Cell Tissue Res. 1980; 206:403-15.
- Coombes RC, et al. Plasma-immunoreactive-calcitonin in patients with non-thyroid tumours. Lancet. 1974; 1:1080-3.
- Dayal Y, et al. Immunocytochemical localization of calcitonin-producing cells in a strumal carcinoid with amyloid stroma. Cancer. 1979; 43:1331-8.
- DeLellis RA, et al. Calcitonin and carcinoembryonic antigen as tumor markers in medullary thyroid carcinoma. Am J Clin Pathol. 1978; 70:587-94.
Specifications
- Reactivity: paraffin
- Control: Thyroid (Cytoplasmic); Thyroid Medullary Carcinoma (Cytoplasmic)
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC22931020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 229R-14 |
| 0.5 mL concentrate | 229R-15 |
| 1.0 mL concentrate | 229R-16 |
| 1.0 mL predilute ready-to-use | 229R-17 |
| 7.0 mL predilute ready-to-use | 229R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 229R-14 |
| 0.5 mL concentrate | 229R-15 |
| 1.0 mL concentrate | 229R-16 |
| 1.0 mL predilute ready-to-use | 229R-17 |
| 7.0 mL predilute ready-to-use | 229R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 229R-14 |
| 0.5 mL concentrate | 229R-15 |
| 1.0 mL concentrate | 229R-16 |
| 1.0 mL predilute ready-to-use | 229R-17 |
| 7.0 mL predilute ready-to-use | 229R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 229R-14-RUO |
| 0.5 mL concentrate (RUO) | 229R-15-RUO |
| 1.0 mL concentrate (RUO) | 229R-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 229R-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 229R-18-RUO |
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