CEA antibody shows a strong cytoplasmic expression in adenocarcinoma cells.
CEA (CEA31) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Updated: 2022-10-13 14:20:29
Anti-CEA is an antibody against carcinoembryonic antigen (CEA), a protein thought to promote tumor development through its role as a cell adhesion molecule. Anti-CEA positivity is seen in adenocarcinomas of many origins, especially colon and lung adenocarcinomas, but rarely seen in mesothelial cells and mesotheliomas. 1-5
- Tron, V et al. "Carcinoembryonic antigen and milk-fat globule protein staining of malignant mesothelioma and adenocarcinoma of the lung." Archives of pathology & laboratory medicine vol. 111,3 (1987): 291-3.
- Abutaily, A S et al. "Immunohistochemistry in the distinction between malignant mesothelioma and pulmonary adenocarcinoma: a critical evaluation of new antibodies." Journal of clinical pathology vol. 55,9 (2002): 662-8.
- Carella, R et al. "Immunohistochemical panels for differentiating epithelial malignant mesothelioma from lung adenocarcinoma: a study with logistic regression analysis." The American journal of surgical pathology vol. 25,1 (2001): 43-50.
- Bhatnagar, Julu et al. "Immunohistochemical detection of carcinoembryonic antigen in esophageal carcinomas: a comparison with other gastrointestinal neoplasms." Anticancer research vol. 22,3 (2002): 1849-57.
- Lagendijk, J H et al. "Immunohistochemical differentiation between primary adenocarcinomas of the ovary and ovarian metastases of colonic and breast origin. Comparison between a statistical and an intuitive approach." Journal of clinical pathology vol. 52,4 (1999): 283-90.
Specifications
- Reactivity: paraffin
- Control: Colon adenocarcinoma (Cytoplasmic); Colon mucosa (Cytoplasmic)
- Dilution Range: 1:100-1:500 *
Package Inserts
IFU
- IVD Rev. 5.0 (CMC23629050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 236M-94 |
| 0.5 mL concentrate | 236M-95 |
| 1.0 mL concentrate | 236M-96 |
| 1.0 mL predilute ready-to-use | 236M-97 |
| 7.0 mL predilute ready-to-use | 236M-98 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 236M-94 |
| 0.5 mL concentrate | 236M-95 |
| 1.0 mL concentrate | 236M-96 |
| 1.0 mL predilute ready-to-use | 236M-97 |
| 7.0 mL predilute ready-to-use | 236M-98 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 236M-94 |
| 0.5 mL concentrate | 236M-95 |
| 1.0 mL concentrate | 236M-96 |
| 1.0 mL predilute ready-to-use | 236M-97 |
| 7.0 mL predilute ready-to-use | 236M-98 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 236M-94-RUO |
| 0.5 mL concentrate (RUO) | 236M-95-RUO |
| 1.0 mL concentrate (RUO) | 236M-96-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 236M-97-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 236M-98-RUO |
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