Burkitt lymphoma is positive for c-Myc.
c-Myc (EP121) Rabbit Monoclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
The oncogenic transcription factor, c-MYC, has a crucial role in growth control, differentiation, cellular metabolism and apoptosis and is associated with variety of tumors.1 c-Myc antibody stains this protein in tissues from colorectal adenocarcinoma,2 breast invasive ductal carcinoma,3 prostate adenocarcinoma,4 Burkitt lymphoma, and diffused large B-cell lymphoma.5
- Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol. 1999; 19:1-11.
- Toon CW, et al. Immunohistochemistry for myc predicts survival in colorectal cancer. PLoS One. 2014; 9:e87456.
- Naidu R, et al. Protein expression and molecular analysis of c-myc gene in primary breast carcinomas using immunohistochemistry and differential polymerase chain reaction. Int J Mol Med. 2002; 9:189-96.
- Yang G, et al. Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression. Cancer. 2005; 103:1186-94.
- Bellan C, et al. Burkitt lymphoma versus diffuse large B-cell lymphoma: a practical approach. Hematol Oncol. 2010; 28:53-6.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: Burkitt lymphoma, prostate carcinoma
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 3.0 (CMC39531030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 395R-14 |
| 0.5 mL concentrate | 395R-15 |
| 1 mL concentrate | 395R-16 |
| 1 mL predilute | 395R-17 |
| 7 mL predilute | 395R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 395R-14 |
| 0.5 mL concentrate | 395R-15 |
| 1 mL concentrate | 395R-16 |
| 1 mL predilute | 395R-17 |
| 7 mL predilute | 395R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 395R-14 |
| 0.5 mL concentrate | 395R-15 |
| 1 mL concentrate | 395R-16 |
| 1 mL predilute | 395R-17 |
| 7 mL predilute | 395R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 395R-14-RUO |
| 0.5 mL concentrate | 395R-15-RUO |
| 1 mL concentrate | 395R-16-RUO |
| 1 mL predilute | 395R-17-RUO |
| 7 mL predilute | 395R-18-RUO |
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