CEA Rabbit Polyclonal Antibody
Specialties: Anatomic Pathology
Anti-CEA is employed essentially as a tool to assist in the distinction between adenocarcinoma and epithelioid malignant mesotheliomas,1 along with other markers such as those against calretinin, CK 5&6, CD15, HBME-1, MOC-31, and Ber-EP4.1 Another suggested use of anti-CEA is to immunophenotype various metastatic adenocarcinomas as a means of identifying their origin within a panel of different markers.1 Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.2,3 Polyclonal anti-CEA is useful in staining hepatocellular carcinoma in a canalicular pattern.2,4
- Shield PW, et al. Immunocytochemical staining of cytologic specimens. How helpful is it? Am J Clin Pathol. 1996; 105:157-62.
- Sheahan K, et al. Differential reactivities of carcinoembryonic antigen (CEA) and CEA-related monoclonal and polyclonal antibodies in common epithelial malignancies. Am J Clin Pathol. 1990; 94:157-64.
- Alkushi A, et al. Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. Virchows Arch. 2003; 442:271-7.
- Morrison C, et al. A comparison of CD10 to pCEA, MOC-31, and hepatocyte for the distinction of malignant tumors in the liver. Mod Pathol. 2002; 15:1279-87.
Specifications
- Reactivity: paraffin
- Control: Colon (Cytoplasmic)
- Dilution Range: 1:200-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC23611040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 236A-14 |
| 0.5 mL concentrate | 236A-15 |
| 1.0 mL concentrate | 236A-16 |
| 1.0 mL predilute ready-to-use | 236A-17 |
| 7.0 mL predilute ready-to-use | 236A-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 236A-14 |
| 0.5 mL concentrate | 236A-15 |
| 1.0 mL concentrate | 236A-16 |
| 1.0 mL predilute ready-to-use | 236A-17 |
| 7.0 mL predilute ready-to-use | 236A-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 236A-14 |
| 0.5 mL concentrate | 236A-15 |
| 1.0 mL concentrate | 236A-16 |
| 1.0 mL predilute ready-to-use | 236A-17 |
| 7.0 mL predilute ready-to-use | 236A-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 236A-14-RUO |
| 0.5 mL concentrate (RUO) | 236A-15-RUO |
| 1.0 mL concentrate (RUO) | 236A-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 236A-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 236A-18-RUO |
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