
Cytokeratin, LMW (AE1) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Anti-cytokeratin, low molecular weight (AE1) antibody labels acidic keratins K10, K14, K15, K16, and K19. Anti-cytokeratin (AE1) reactivity is seen in most normal and neoplastic cells of epithelial origin. Anti-cytokeratin (AE1) is a useful immunohistochemical reagent for distinguishing between poorly differentiated carcinomas and non-epithelial neoplasms.1-5
- Tyler, CR. Immunoperoxidase techniques: practical and theoretical aspects. Arch Pathol Lab Med. 1978; 102:113-21.
- Weiss RA, et al. Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes. J Cell Biol 1984; 98:1397-406.
- Swanson PE, et al. Heffalumps, jagulars, and cheshire cats. A commentary on cytokeratins and soft tissue sarcomas. Am J Clin Pathol 1991; 95:S2-7.
- Eusebi V, et al. Keratin-positive epithelioid angiosarcoma of thyroid. A report of four cases. Am J Clin Pathol. 1990; 14:737-47.
- Dabbs DJ. Diagnostic Immunohistochemistry. Churchhill Livingstone. 2002; 166-74.
- Lopez-Beltran A, et al. Lymphoepithelioma-like carcinoma of the urinary bladder: a clinicopathologic study of 13 cases. Virchows Arch. 2001; 438:552-7.
- Kitazawa R, et al. In situ demonstration of parathyroid hormone-related protein mRNA in sclerosing hepatic carcinoma. Virchows Arch. 1999; 435:137-42.
- Judkins AR, et al. Sensitivity and specificity of antibodies on necrotic tumor tissue. Am J Clin Pathol. 1998; 110:641-6.
- Demetris AJ, et al. Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes. Am J Pathol. 1996; 149:439-48.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: prostate, salivary gland
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC30121040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
0.1 mL concentrate | 301M-14 |
0.5 mL concentrate | 301M-15 |
1 mL concentrate | 301M-16 |
1 mL predilute | 301M-17 |
7 mL predilute | 301M-18 |
For in vitro diagnostic (IVD) use in Canada
0.1 mL concentrate | 301M-14 |
0.5 mL concentrate | 301M-15 |
1 mL concentrate | 301M-16 |
1 mL predilute | 301M-17 |
7 mL predilute | 301M-18 |
For in vitro diagnostic (IVD) use in Europe
0.1 mL concentrate | 301M-14 |
0.5 mL concentrate | 301M-15 |
1 mL concentrate | 301M-16 |
1 mL predilute | 301M-17 |
7 mL predilute | 301M-18 |
For research use only (RUO) in Japan
0.1 mL concentrate | 301M-14-RUO |
0.5 mL concentrate | 301M-15-RUO |
1 mL concentrate | 301M-16-RUO |
1 mL predilute | 301M-17-RUO |
7 mL predilute | 301M-18-RUO |
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