Scattered T-lymphocytes express CD5 antigen in a cytoplasmic staining reaction.
CD5 (4C7) Mouse Monoclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells. CD5 expression is useful in distinguishing mature T-cell neoplasms and differentiating among mature small lymphoid cell malignancies. Anti-CD5 does not react with granulocytes or monocytes.1-7
- Chan JK, et al., A proposal for classification of lymphoid neoplasms (by the International Lymphoma Study Group). Histopathology. 1994; 25:517-36.
- Kasaian MT, et al. CD5 + B lymphocytes. Proc Soc Exp Bio and Med. 1991; 197:226-41.
- Jones NH, et al, Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1. Nature. 1986; 323:346-9.
- Tan SH, et al. Cutaneous lymphomas other than mycosis fungoides in Singapore: a clinicopathological analysis using recent classification systems. Br J Dermatol. 2003; 149:542-53.
- Chang CC, et al. CD5+ T-cell/histiocyte-rich large B-cell lymphoma. Mod Pathol. 2002; 15:1051-7.
- Hatano B, et al. Peripheral T-cell lymphoma with a nodular growth pattern. Pathol Int. 2002; 52:400-5.
- West RB, et al. The usefulness of immunohistochemistry in the diagnosis of follicular lymphoma in bone marrow biopsy specimens. Am J Clin Pathol. 2002; 117:636-43.
Specifications
- Reactivity: paraffin
- Visualization: membranous
- Control: tonsil, lymph node
- Dilution Range: 1:10-1:50*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC20521040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 205M-14 |
| 0.5 mL concentrate | 205M-15 |
| 1 mL concentrate | 205M-16 |
| 1 mL predilute | 205M-17 |
| 7 mL predilute | 205M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 205M-14 |
| 0.5 mL concentrate | 205M-15 |
| 1 mL concentrate | 205M-16 |
| 1 mL predilute | 205M-17 |
| 7 mL predilute | 205M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 205M-14 |
| 0.5 mL concentrate | 205M-15 |
| 1 mL concentrate | 205M-16 |
| 1 mL predilute | 205M-17 |
| 7 mL predilute | 205M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 205M-14-RUO |
| 0.5 mL concentrate | 205M-15-RUO |
| 1 mL concentrate | 205M-16-RUO |
| 1 mL predilute | 205M-17-RUO |
| 7 mL predilute | 205M-18-RUO |
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