CD2 (EP222) Rabbit Monoclonal Antibody
Specialties: Hematopathology
CD2 is one of the earliest T-cell lineage restricted antigens to appear during T-cell differentiation and only rare CD2+ cells can be found in the bone marrow. Anti-CD2 is a pan-T-cell antigen marker. Anti-CD2 is therefore useful for the identification of virtually all normal T-lymphocytes. It is also very useful in the assessment of lymphoid malignancies as it is expressed in the majority of precursor and mature T-cell lymphomas and leukemias. As with other pan-T-cell antigens, CD2 may be aberrantly deleted in some neoplastic T-cell populations, especially peripheral T-cell lymphomas. When combined with anti-CD25, anti-CD2 may assist in the identification of systemic mastocytosis and mastocytic leukemia.1-4
- Aguilera NS, et al. Arch Pathol Lab Med. 2006; 130:1772-9.
- Barrionuevo C, et al. Appl Immunohistochem Mol Morphol. 2007; 15:38-44.
- Bovenschen HJ, et al. Br J Dermatol. 2005; 153:72-8.
- Foon KA, et al. Blood 1986; 68:1- 31.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: tonsil
- Dilution Range: 1:50-1:200*
Package Inserts
IFU
- IVD Rev. 1.0 (CMC10231010)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 102R-14 |
| 0.5 mL concentrate | 102R-15 |
| 1 mL concentrate | 102R-16 |
| 1 mL predilute | 102R-17 |
| 7 mL predilute | 102R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 102R-14 |
| 0.5 mL concentrate | 102R-15 |
| 1 mL concentrate | 102R-16 |
| 1 mL predilute | 102R-17 |
| 7 mL predilute | 102R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 102R-14 |
| 0.5 mL concentrate | 102R-15 |
| 1 mL concentrate | 102R-16 |
| 1 mL predilute | 102R-17 |
| 7 mL predilute | 102R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 102R-14-RUO |
| 0.5 mL concentrate | 102R-15-RUO |
| 1 mL concentrate | 102R-16-RUO |
| 1 mL predilute | 102R-17-RUO |
| 7 mL predilute | 102R-18-RUO |
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