CD7 (MRQ-56) Mouse Monoclonal Antibody
Specialties: Hematopathology Anatomic Pathology
CD7 antigen is a 40-kDa cell surface glycoprotein that is a member of the immunoglobulin gene superfamily.1,2 While its precise function is not known, it is suggested that CD7 plays a role in T-cell interactions as it is one of the earliest T-cell lineage associated antigens expressed during T-cell ontogeny.2,3 CD7 is expressed in thymocytes, mature peripheral T-cells, natural killer cells, and lymphoid and myeloid progenitors.1,2,4
- Stillwell R, et al. T cell signal transduction and the role of CD7 in costimulation. Immunol Res. 2001; 24:31-52.
- Schanberg LE, et al. Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene. Proc Natl Acad Sci USA. 1991; 88:603-7.
- Chabannon C, et al. Expression of CD7 on normal human myeloid progenitors. J Immunol. 1992; 149:2110-3.
- Rabinowich H, et al. Expression and function of CD7 molecule on human natural killer cells. J Immunol. 2003; 152: 517-26.
Specifications
- Reactivity: paraffin
- Visualization: membranous
- Control: tonsil, peripheral T-cell lymphoma
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC10722020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 107M-24 |
| 0.5 mL concentrate | 107M-25 |
| 1 mL concentrate | 107M-26 |
| 1 mL predilute | 107M-27 |
| 7 mL predilute | 107M-28 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 107M-24 |
| 0.5 mL concentrate | 107M-25 |
| 1 mL concentrate | 107M-26 |
| 1 mL predilute | 107M-27 |
| 7 mL predilute | 107M-28 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 107M-24 |
| 0.5 mL concentrate | 107M-25 |
| 1 mL concentrate | 107M-26 |
| 1 mL predilute | 107M-27 |
| 7 mL predilute | 107M-28 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 107M-24-RUO |
| 0.5 mL concentrate | 107M-25-RUO |
| 1 mL concentrate | 107M-26-RUO |
| 1 mL predilute | 107M-27-RUO |
| 7 mL predilute | 107M-28-RUO |
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