CD5 (EP77) Rabbit Monoclonal Antibody
Specialties: Hematopathology
Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma.1,2 CD5 aberrant expression is useful in identification of mature T-cell neoplasms.3,4,5 Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23.1,3 Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies.1,6 In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.1,2
- Chan JKC, et al. Histopathology. 1994; 25:517-536.
- Jones NH, et al. Nature. 1986; 323:346-349.
- Tan SH, et al. Br J Dermatol. 2003; 149:542-53.
- Chang CC, et al. Mod Pathol. 2002; 15:1051-7.
- Hatano B, et al. Pathol Int. 2002; 52:400-5.
- West RB, et al. Am J Clin Pathol. 2002; 117:636-43.
Specifications
- Reactivity: paraffin
- Visualization: membranous
- Control: tonsil, lymph node
- Dilution Range: 1:50-1:100*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC20532020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 205R-24 |
| 0.5 mL concentrate | 205R-25 |
| 1 mL concentrate | 205R-26 |
| 1 mL predilute | 205R-27 |
| 7 mL predilute | 205R-28 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 205R-24 |
| 0.5 mL concentrate | 205R-25 |
| 1 mL concentrate | 205R-26 |
| 1 mL predilute | 205R-27 |
| 7 mL predilute | 205R-28 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 205R-24 |
| 0.5 mL concentrate | 205R-25 |
| 1 mL concentrate | 205R-26 |
| 1 mL predilute | 205R-27 |
| 7 mL predilute | 205R-28 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 205R-24-RUO |
| 0.5 mL concentrate | 205R-25-RUO |
| 1 mL concentrate | 205R-26-RUO |
| 1 mL predilute | 205R-27-RUO |
| 7 mL predilute | 205R-28-RUO |
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