CD30 (Ber-H2) Mouse Monoclonal Antibody
Specialties: Hematopathology
Anti-CD30 detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders,1-3 and in embryonal carcinomas.4 Occasionally diffuse large B-cell lymphoma stains with this antibody.3 This antibody also stains plasma cells in paraffin-embedded tissue as well as reactive immunoblasts. The staining pattern of anti-CD30 in lymphoma and embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only.4
- Schwarting R, et al. BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol-resistant epitope. Blood. 1989; 74:1678-89.
- George DH, et al. Primary anaplastic large cell lymphoma of the central nervous system: prognostic effect of ALK-1 expression. Am J Surg Pathol. 2003; 27:487-93.
- Hedvat CV, et al. Application of tissue microarray technology to the study of non-Hodgkin's and Hodgkin's Lymphoma. Hum Pathol. 2002; 33:968-74.
- Dabbs DJ. Diagnostic Immunohistochemistry Theranostic and Genomic Applications. 4th Edition Saunders Elsevier. 2014; p702.
Specifications
- Reactivity: paraffin
- Control: Classic Hodgkin Lymphoma (Membranous); Lymphoma (Membranous)
- Dilution Range: 1:50-1:200 *
Package Inserts
IFU
- IVD Rev. 4.0 (CMC13029040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 130M-94 |
| 0.5 mL concentrate | 130M-95 |
| 1.0 mL concentrate | 130M-96 |
| 1.0 mL predilute ready-to-use | 130M-97 |
| 7.0 mL predilute ready-to-use | 130M-98 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 130M-94 |
| 0.5 mL concentrate | 130M-95 |
| 1.0 mL concentrate | 130M-96 |
| 1.0 mL predilute ready-to-use | 130M-97 |
| 7.0 mL predilute ready-to-use | 130M-98 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 130M-94 |
| 0.5 mL concentrate | 130M-95 |
| 1.0 mL concentrate | 130M-96 |
| 1.0 mL predilute ready-to-use | 130M-97 |
| 7.0 mL predilute ready-to-use | 130M-98 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 130M-94-RUO |
| 0.5 mL concentrate (RUO) | 130M-95-RUO |
| 1.0 mL concentrate (RUO) | 130M-96-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 130M-97-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 130M-98-RUO |
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