PAX-5 (24) Mouse Monoclonal Antibody
Specialties: Hematopathology
PAX-5 encodes for B-cell-specific activator protein (BSAP), a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5.4 PAX-5 is not detected in multiple myeloma and solitary plasmacytoma, making it useful for such differentiation.1,3 Diffuse large B-cell lymphomas do express PAX-5, save for those with terminal B-cell differentiation. T-cell neoplasms do not stain with anti-PAX-5. There is a strong association with CD20 expression.1-4
- Torlakovic E, et al. Am J Surg Pathol. 2002; 26:1343-50.
- Willenbrock K, et al. Lab Invest. 2002; 82:1103-9.
- Falini B, et al. Blood. 2002; 99:409-26.
- Schwering I, et al. Blood. 2003; 101:1505-12.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: tonsil
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC31221040)
Have a different keycode?
Click Here
Learn how to obtain your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 312M-14 |
| 0.5 mL concentrate | 312M-15 |
| 1 mL concentrate | 312M-16 |
| 1 mL predilute | 312M-17 |
| 7 mL predilute | 312M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 312M-14 |
| 0.5 mL concentrate | 312M-15 |
| 1 mL concentrate | 312M-16 |
| 1 mL predilute | 312M-17 |
| 7 mL predilute | 312M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 312M-14 |
| 0.5 mL concentrate | 312M-15 |
| 1 mL concentrate | 312M-16 |
| 1 mL predilute | 312M-17 |
| 7 mL predilute | 312M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 312M-14-RUO |
| 0.5 mL concentrate | 312M-15-RUO |
| 1 mL concentrate | 312M-16-RUO |
| 1 mL predilute | 312M-17-RUO |
| 7 mL predilute | 312M-18-RUO |
To request information on this product in additional countries, please click the button below.
