PD-L1 Analyte ControlDR
PD-L1 Analyte ControlDR consists of four different cell lines with PD-L1 expression levels of negative, low, medium, and high. Ideal for use as a same slide control for PD-L1 to demonstrate the sensitivity of the assay and improve confidence in the result.
PD-L1, also known as CD274 and B7 homolog 1 (B7-H1), is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in supressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer’s ability to evade the immune system.
Specifications
- Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
- Pre-cut sections are cut at 4µm, mounted on positively charged slides and baked overnight at 37°C.
- Cell microarrays (CMA) contain cores that are 2mm in diameter and 3-3.5mm in length. It is possible to obtain over 300-400 sections depending on thickness.
Package Inserts
IFU
Ordering Information
For research use only (RUO) in USA
| 2 unstained slides | HCL019 |
| 5 unstained slides | HCL020 |
| 1 cell microarray block | HCL021 |
For research use only (RUO) in Europe
| 2 unstained slides | HCL019 |
| 5 unstained slides | HCL020 |
| 1 cell microarray block | HCL021 |
For research use only (RUO) in Japan
| 2 unstained slides | HCL019 |
| 5 unstained slides | HCL020 |
| 1 cell microarray block | HCL021 |
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