NSE antibody expresses pancreatic neuroendocrine tumors in a cytoplasmic pattern.
NSE (MRQ-55) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Updated: 2022-12-23 09:19:24
Neuron-specific enolase (NSE) is a glycolytic isoenzyme of the enolase gamma-gamma dimer selectively detected in neurons, peripheral nerves, some neuroendocrine cells and tumors.1-3. NSE immunoreactivity is also observed, to a lesser extent, in smooth muscle tissue.4 Anti-NSE is often used to visualize peripheral nerves and for the identification of neuroendocrine differentiation.5
- Wick MR, et al. Neuron-specific enolase in neuroendocrine tumors of the thymus, bronchus and skin. Am J Clin Pathol. 1983; 79:703-7.
- Vinores SA, et al. Immunohistochemical demonstration of neuron-specific enolase in neoplasms of the CNS and other tissues. Arch Pathol Lab Med. 1984; 108:536-40.
- Leong AS, et al. Criteria for the diagnosis of primary endocrine carcinoma of the skin (Merkel cell carcinoma). A histological, immunohistochemical and ultrastructural study of 13 cases. Pathology. 1986; 18:393-9.
- Cooper EH. Neuron-specific enolase. Int J Biol Markers. 1994; 9:205-10.
- Leonard N, et al. Neuroproliferation in the mucosa is a feature of coeliac disease and Crohn's disease. Gut. 1995; 37:763-5.
Specifications
- Reactivity: paraffin
- Control: Pancreas (Cytoplasmic); Carcinoid tumor (Cytoplasmic)
- Dilution Range: 1:50-1:200 *
Package Inserts
IFU
- IVD Rev. 3.0 (CMC30622030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 306M-24 |
| 0.5 mL concentrate | 306M-25 |
| 1.0 mL concentrate | 306M-26 |
| 1.0 mL predilute ready-to-use | 306M-27 |
| 7.0 mL predilute ready-to-use | 306M-28 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 306M-24 |
| 0.5 mL concentrate | 306M-25 |
| 1.0 mL concentrate | 306M-26 |
| 1.0 mL predilute ready-to-use | 306M-27 |
| 7.0 mL predilute ready-to-use | 306M-28 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 306M-24 |
| 0.5 mL concentrate | 306M-25 |
| 1.0 mL concentrate | 306M-26 |
| 1.0 mL predilute ready-to-use | 306M-27 |
| 7.0 mL predilute ready-to-use | 306M-28 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 306M-24-RUO |
| 0.5 mL concentrate (RUO) | 306M-25-RUO |
| 1.0 mL concentrate (RUO) | 306M-26-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 306M-27-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 306M-28-RUO |
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