GCDFP-15 (23A3) + Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Monoclonal Antibodies
Specialties: Breast/Gynecological Pathology
Anti-GCDFP-15, mouse monoclonal (23A3), and anti-mammaglobin, mouse monoclonal (304-1A5) and rabbit monoclonal (31A5), is an antibody cocktail. GCDFP-15 is a 15 kDa glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal. Mammaglobin (10 kDa) is a breast-associated glycoprotein distantly related to the secretoglobin family that includes human uteroglobin and lipophilin.1-6 This antibody cocktail is useful in identifying breast carcinoma.4-6
- Cohen, C et al. Mammary Paget’s disease and associated carcinoma. An immunohistochemical study. Arch Pathol Lab Med. 1993; 117:291-4.
- Bhargava R, et al. Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol. 2007; 127:103-13.
- Tornos C, et al. Expression of WT1, CA 125, and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomas versus metastatic breast cancer to the ovary. Am J Surg Pathol. 2005; 29:1482-9.
- Takeda Y, et al. Analysis of expression patterns of breast cancer-specific markers (mammaglobin and gross cystic disease fluid protein 15) in lung and pleural tumors. Arch Pathol Lab Med. 2008; 132:239-43.
- Liegl, B et al. Mammary and extramammary Paget’s disease: an immunohistochemical study of 83 cases. Histopathology. 2007; 50:439-47.
- Watson MA, et al. Mammaglobin expression in primary, metastatic, and occult breast cancer. Cancer Res. 1999; 59:3028-31.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: breast, breast carcinoma
Package Inserts
IFU
- IVD Rev. 6.0 (CMC90640060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 1 mL predilute | 906H-07 |
| 7 mL predilute | 906H-08 |
For in vitro diagnostic (IVD) use in Canada
| 1 mL predilute | 906H-07 |
| 7 mL predilute | 906H-08 |
For in vitro diagnostic (IVD) use in Europe
| 1 mL predilute | 906H-07 |
| 7 mL predilute | 906H-08 |
For research use only (RUO) in Japan
| 1 mL predilute | 906H-07-RUO |
| 7 mL predilute | 906H-08-RUO |
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