E-cadherin (EP700Y) Rabbit Monoclonal Primary Antibody
Specialties: Breast/Gynecological Pathology
E-cadherin is a transmembrane protein that is involved in cell adhesion through the formation of adherens junctions between cells. It is expressed in cells of epithelial lineage. Anti-E-cadherin stains positively in glandular epithelium as well as carcinomas of the gastrointestinal tract1 and breast. E-cadherin immunohistochemistry may also aid in the differentiation of breast ductal carcinomas (with membranous stain) from lobular carcinomas (with loss of the membranous stain)2,3.
- Karayiannakis, A J et al. "E-cadherin expression as a differentiation marker in gastric cancer." Hepato-gastroenterology vol. 45,24 (1998): 2437-42.
- Wahed, Amer et al. "E-cadherin expression in pleomorphic lobular carcinoma: an aid to differentiation from ductal carcinoma." Annals of diagnostic pathology vol. 6,6 (2002): 349-51.
- Acs, G et al. "Differential expression of E-cadherin in lobular and ductal neoplasms of the breast and its biologic and diagnostic implications." American journal of clinical pathology vol. 115,1 (2001): 85-98.
Specifications
- Reactivity: paraffin
- Control: Breast (Membranous)
- Dilution Range: 1:50-1:200 *
Package Inserts
IFU
- IVD Rev. 6.0 (CMC24631060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 246R-14 |
| 0.5 mL concentrate | 246R-15 |
| 1.0 mL concentrate | 246R-16 |
| 1.0 mL predilute ready-to-use | 246R-17 |
| 7.0 mL predilute ready-to-use | 246R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 246R-14 |
| 0.5 mL concentrate | 246R-15 |
| 1.0 mL concentrate | 246R-16 |
| 1.0 mL predilute ready-to-use | 246R-17 |
| 7.0 mL predilute ready-to-use | 246R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 246R-14 |
| 0.5 mL concentrate | 246R-15 |
| 1.0 mL concentrate | 246R-16 |
| 1.0 mL predilute ready-to-use | 246R-17 |
| 7.0 mL predilute ready-to-use | 246R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 246R-14-RUO |
| 0.5 mL concentrate (RUO) | 246R-15-RUO |
| 1.0 mL concentrate (RUO) | 246R-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 246R-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 246R-18-RUO |
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