FLI-1 (MRQ-1) Mouse Monoclonal Antibody
Specialties: Soft Tissue Pathology
Friend leukemia integration 1 transcription factor (FLI-1) is a protein encoded by the proto-ocogene FLI-1. The FLI-1 protein is best known for its critical role in the pathogenesis of ES/pPNET. FLI-1 is normally expressed in endothelial cells and in hematopoietic cells, including T-lymphocytes. The immunohistochemical detection of FLI-1 protein has been shown in studies to be valuable in the discrimination of Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) from most of its potential mimics. ES/pPNET is a rare primary tumor of the bone/soft tissue that resembles other undifferentiated tumors.1-3
- Mhawech-Fauceglia P, et al. Histopathology. 2006; 49:569-75.
- Kuroda N, et al. Med Mol Morphol. 2006; 39:221-5.
- Ellison DA, et al. Hum Pathol. 2007; 38:205-11.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: primitive neuroectodermal tumor
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC25421040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 254M-14 |
| 0.5 mL concentrate | 254M-15 |
| 1 mL concentrate | 254M-16 |
| 1 mL predilute | 254M-17 |
| 7 mL predilute | 254M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 254M-14 |
| 0.5 mL concentrate | 254M-15 |
| 1 mL concentrate | 254M-16 |
| 1 mL predilute | 254M-17 |
| 7 mL predilute | 254M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 254M-14 |
| 0.5 mL concentrate | 254M-15 |
| 1 mL concentrate | 254M-16 |
| 1 mL predilute | 254M-17 |
| 7 mL predilute | 254M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 254M-14-RUO |
| 0.5 mL concentrate | 254M-15-RUO |
| 1 mL concentrate | 254M-16-RUO |
| 1 mL predilute | 254M-17-RUO |
| 7 mL predilute | 254M-18-RUO |
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