Nuclear labelling of rhabdomyosarcoma cells by myogenin antibody.
Myogenin (F5D) Mouse Monoclonal Antibody
Specialties: Pediatric Pathology Soft Tissue Pathology
Updated: 2022-12-23 08:54:46
Myogenin also identified as myogenic factor 4 is a muscle specific transcription factor associated with muscle differentiation and cell cycle.1 Anti-myogenin reactivity is seen in the nuclei of myoblasts in developing muscle tissue. Anti-myogenin is a useful immunohistochemical reagent for identification of rhabdomyosarcoma.2-5
- Miller JB. Myogenic programs of mouse muscle cell lines: expression of myosin heavy chain isoforms, MyoD1, and myogenin. J Cell Biol. 1990; 111:1149-59.
- Wang NP, et al. Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood. Am J Pathol. 1995; 147:1799-810.
- Cui S, et al. Evaluation of new monoclonal anti-MyoD1 and anti-myogenin antibodies for the diagnosis of rhabdomyosarcoma. Pathol Int. 1999; 49:62-8.
- Kaspar et al. The expression of c-Myb correlates with the levels of rhabdomyosarcoma-specific marker myogenin. Sci Rep. 2015; 5:15090.
- Rudzinski et al. Myogenin, AP 2 Beta, NOS-1 and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma. Am J Surg Pathol. 2014; 38:654-9.
Specifications
- Reactivity: paraffin
- Control: Rhabdomyosarcoma (Nuclear)
- Dilution Range: 1:25-1:100 *
Package Inserts
IFU
- IVD Rev. 5.0 (CMC29621050)
Have a different keycode?
Click Here
Learn how to obtain your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 296M-14 |
| 0.5 mL concentrate | 296M-15 |
| 1.0 mL concentrate | 296M-16 |
| 1.0 mL predilute ready-to-use | 296M-17 |
| 7.0 mL predilute ready-to-use | 296M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 296M-14 |
| 0.5 mL concentrate | 296M-15 |
| 1.0 mL concentrate | 296M-16 |
| 1.0 mL predilute ready-to-use | 296M-17 |
| 7.0 mL predilute ready-to-use | 296M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 296M-14 |
| 0.5 mL concentrate | 296M-15 |
| 1.0 mL concentrate | 296M-16 |
| 1.0 mL predilute ready-to-use | 296M-17 |
| 7.0 mL predilute ready-to-use | 296M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 296M-14-RUO |
| 0.5 mL concentrate (RUO) | 296M-15-RUO |
| 1.0 mL concentrate (RUO) | 296M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 296M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 296M-18-RUO |
To request information on this product in additional countries, please click the button below.
