Alpha-fetoprotein antibody picks up fetal liver cells in a strong cytoplasmic staining reaction.
Alpha-Fetoprotein Rabbit Polyclonal Antibody
Specialties: Anatomic Pathology Genitourinary (GU) Pathology
Updated: 2023-05-01 08:38:59
Alpha-fetoprotein (AFP) is a fetal tumor-associated polypeptide of the albuminoid gene family that binds and transports molecules in addition to many other proposed functions.1 This secretory protein is produced by the fetal yolk sac and liver but is found only in trace amounts in adult liver.2 AFP expression by immunohistochemistry is seen in hepatocellular carcinoma (HCC).3
- Mizejewski, G J. "Alpha-fetoprotein structure and function: relevance to isoforms, epitopes, and conformational variants." Experimental biology and medicine (Maywood, N.J.) vol. 226,5 (2001): 377-408.
- Lazarevich, N L. "Molecular mechanisms of alpha-fetoprotein gene expression." Biochemistry. Biokhimiia vol. 65,1 (2000): 117-33.
- Yusof, Yasmin Anum Mohd et al. "Immunohistochemical expression of pi class glutathione S-transferase and alpha-fetoprotein in hepatocellular carcinoma and chronic liver disease." Analytical and quantitative cytology and histology vol. 25,6 (2003): 332-8.
Specifications
- Reactivity: paraffin
- Control: Fetal Liver (Cytoplasmic)
- Dilution Range: 1:50-1:200 *
Package Inserts
IFU
- IVD Rev. 6.0 (CMC20311060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 203A-14 |
| 0.5 mL concentrate | 203A-15 |
| 1.0 mL concentrate | 203A-16 |
| 1.0 mL predilute ready-to-use | 203A-17 |
| 7.0 mL predilute ready-to-use | 203A-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 203A-14 |
| 0.5 mL concentrate | 203A-15 |
| 1.0 mL concentrate | 203A-16 |
| 1.0 mL predilute ready-to-use | 203A-17 |
| 7.0 mL predilute ready-to-use | 203A-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 203A-14 |
| 0.5 mL concentrate | 203A-15 |
| 1.0 mL concentrate | 203A-16 |
| 1.0 mL predilute ready-to-use | 203A-17 |
| 7.0 mL predilute ready-to-use | 203A-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 203A-14-RUO |
| 0.5 mL concentrate (RUO) | 203A-15-RUO |
| 1.0 mL concentrate (RUO) | 203A-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 203A-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 203A-18-RUO |
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