Melanoma labelled by tyrosinase antibody.
Tyrosinase (T311) Mouse Monoclonal Antibody
Specialties: Dermatopathology
Updated: 2017-05-24 08:46:09
Tyrosinase is an enzyme, amongst a family of enzymes, which is involved in the biosynthesis of melanin. It is a highly specific and sensitive marker for melanocytic differentiation, and has been found to be quite specific for melanotic lesions such as malignant melanoma.1-3
- Jungbluth AA, et al. T311--an anti-tyrosinase monoclonal antibody for the detection of melanocytic lesions in paraffin embedded tissues. Pathol Res Pract. 2000; 196:235-42.
- Ordóñez NG. Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update. Hum Pathol. 2014; 45:191-205.
- Jaanson N, et al. Identification of the immunodominant regions of the melanoma antigen tyrosinase by anti-tyrosinase monoclonal antibodies. Melanoma Res. 2003. 13:473-82.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: melanoma, skin
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC34429040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 344M-94 |
| 0.5 mL concentrate | 344M-95 |
| 1 mL concentrate | 344M-96 |
| 1 mL predilute | 344M-97 |
| 7 mL predilute | 344M-98 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 344M-94 |
| 0.5 mL concentrate | 344M-95 |
| 1 mL concentrate | 344M-96 |
| 1 mL predilute | 344M-97 |
| 7 mL predilute | 344M-98 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 344M-94 |
| 0.5 mL concentrate | 344M-95 |
| 1 mL concentrate | 344M-96 |
| 1 mL predilute | 344M-97 |
| 7 mL predilute | 344M-98 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 344M-94-RUO |
| 0.5 mL concentrate | 344M-95-RUO |
| 1 mL concentrate | 344M-96-RUO |
| 1 mL predilute | 344M-97-RUO |
| 7 mL predilute | 344M-98-RUO |
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