Pituitary cells express anti-ACTH in the cytoplasm.
ACTH Rabbit Polyclonal Antibody
Specialties: Anatomic Pathology Neuropathology
Updated: 2017-05-24 08:46:09
ACTH or Adrenocorticotropic hormone is synthesized from pre-pro-opiomelanocortin (pre-POMC). ACTH is produced and secreted from corticotrophs in the anterior lobe (or adenohypophysis) of the pituitary gland. The anti-ACTH immunohistochemical reagent could be useful in the study of neoplastic and non-neoplastic pituitary diseases.1-4
- Pizarro CB, et al. Measurement of Ki-67 antigen in 159 pituitary adenomas using the MIB-1 monoclonal antibody. Braz J Med Biol Res. 2004; 37:235-43.
- Kageyama K, et al. A multihormonal pituitary adenoma with growth hormone and adrenocorticotropic hormone production, causing acromegaly and Cushing disease. Am J Med Sci. 2002; 324:326-30.
- Fan X, et al. Immunohistochemical localization of carboxypeptidases D, E, and Z in pituitary adenomas and normal human pituitary. J Histochem Cytochem. 2002; 50:1509-16.
- Japon MA, et al. Glial-derived neurotropic factor and RET gene expression in normal human anterior pituitary cell types and in pituitary tumors. J Clin Endocrinol Metab. 2002; 87:1879-84.
Specifications
- Reactivity: paraffin
- Control: pituitary (cytoplasmic)
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC20617040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 206A-74 |
| 0.5 mL concentrate | 206A-75 |
| 1 mL concentrate | 206A-76 |
| 1 mL predilute | 206A-77 |
| 7 mL predilute | 206A-78 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 206A-74 |
| 0.5 mL concentrate | 206A-75 |
| 1 mL concentrate | 206A-76 |
| 1 mL predilute | 206A-77 |
| 7 mL predilute | 206A-78 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 206A-74 |
| 0.5 mL concentrate | 206A-75 |
| 1 mL concentrate | 206A-76 |
| 1 mL predilute | 206A-77 |
| 7 mL predilute | 206A-78 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 206A-74-RUO |
| 0.5 mL concentrate | 206A-75-RUO |
| 1 mL concentrate | 206A-76-RUO |
| 1 mL predilute | 206A-77-RUO |
| 7 mL predilute | 206A-78-RUO |
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