Factor XIIIa (AC-1A1) Mouse Monoclonal Antibody
Specialties: Dermatopathology
Factor XIIIa is a plasma transglutaminase that is part of the blood coagulation cascade and plays a critical role in stabilizing fibrin networks at the site of an injury to produce a clot. Factor XIIIa is expressed in platelets, megakaryocytes, fibroblast-like cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-Factor XIIIa immunohistochemistry is used to identify fibrohistiocytic neoplasms such as dermatofibroma.1-3
- Abenoza, P, and T Lillemoe. "CD34 and factor XIIIa in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans." The American Journal of dermatopathology vol. 15,5 (1993): 429-34.
- Horenstein, M G et al. "Indeterminate fibrohistiocytic lesions of the skin: is there a spectrum between dermatofibroma and dermatofibrosarcoma protuberans?." The American journal of surgical pathology vol. 24,7 (2000): 996-1003.
- Kraus, M D et al. ""Juvenile" xanthogranuloma: an immunophenotypic study with a reappraisal of histogenesis." The American Journal of dermatopathology vol. 23,2 (2001): 104-11.
Specifications
- Reactivity: paraffin
- Control: Dermatofibroma (Cytoplasmic)
- Dilution Range: 1:100-1:500 *
Package Inserts
IFU
- IVD Rev. 5.0 (CMC25121050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 251M-14 |
| 0.5 mL concentrate | 251M-15 |
| 1.0 mL concentrate | 251M-16 |
| 1.0 mL predilute ready-to-use | 251M-17 |
| 7.0 mL predilute ready-to-use | 251M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 251M-14 |
| 0.5 mL concentrate | 251M-15 |
| 1.0 mL concentrate | 251M-16 |
| 1.0 mL predilute ready-to-use | 251M-17 |
| 7.0 mL predilute ready-to-use | 251M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 251M-14 |
| 0.5 mL concentrate | 251M-15 |
| 1.0 mL concentrate | 251M-16 |
| 1.0 mL predilute ready-to-use | 251M-17 |
| 7.0 mL predilute ready-to-use | 251M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 251M-14-RUO |
| 0.5 mL concentrate (RUO) | 251M-15-RUO |
| 1.0 mL concentrate (RUO) | 251M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 251M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 251M-18-RUO |
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