Anti-SALL4 labels the nuclei of seminoma tumor cells.
SALL4 (6E3) Mouse Monoclonal Antibody
Specialties: Genitourinary (GU) Pathology
Updated: 2022-10-13 11:15:59
Sal-like protein 4 (SALL4) is a zinc-finger transcription factor1 that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities.2 SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas.1 SALL4 expression is also seen in the spermatogonia of normal testis.
- Miettinen M, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014; 38:410-20.
- Yang J, et al. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. PNAS. 2008; 105:19756-61.
Specifications
- Reactivity: paraffin
- Control: Seminoma, dysgerminoma (Nuclear)
- Dilution Range: 1:25-1:100 *
Package Inserts
IFU
- IVD Rev. 3.0 (CMC38521030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 385M-14 |
| 0.5 mL concentrate | 385M-15 |
| 1.0 mL concentrate | 385M-16 |
| 1.0 mL predilute ready-to-use | 385M-17 |
| 7.0 mL predilute ready-to-use | 385M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 385M-14 |
| 0.5 mL concentrate | 385M-15 |
| 1.0 mL concentrate | 385M-16 |
| 1.0 mL predilute ready-to-use | 385M-17 |
| 7.0 mL predilute ready-to-use | 385M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 385M-14 |
| 0.5 mL concentrate | 385M-15 |
| 1.0 mL concentrate | 385M-16 |
| 1.0 mL predilute ready-to-use | 385M-17 |
| 7.0 mL predilute ready-to-use | 385M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 385M-14-RUO |
| 0.5 mL concentrate (RUO) | 385M-15-RUO |
| 1.0 mL concentrate (RUO) | 385M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 385M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 385M-18-RUO |
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