Cell Marque Portfolio

PSA (ER-PR8)

Mouse Monoclonal


Prostate-Specific Antigen (PSA) is a 33 kDa protein primarily produced by the prostatic epithelium and the epithelial lining of the periurethral glands 1. PSA is strongly expressed in both normal and neoplastic prostatic tissue. Although PSA can be considered prostate-specific, PSA and/or PSA gene expression has been detected at low levels in some extra-prostatic tissues such as normal breast tissue, breast tumors, endometrium, adrenal neoplasms and renal cell carcinomas 1, 2, 3. Anti-PSA is most useful in determining the prostatic origin of carcinomas in non-prostate tissues (metastatic disease) using IHC techniques.   This product is best used in conjunction with a panel of antibodies as, up to 27% of prostate carcinoma cases (predominantly poorly differentiated carcinomas) can be negative for this marker.4

Specialties: Anatomic Pathology Genitourinary (GU) Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: prostate, prostate carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:50-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(24min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

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Last updated: 2016-01-07 14:13:45

PSA
Benign prostate gland epithelial cells are labelled with PSA antibody.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: prostate, prostate carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:50-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(24min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 324M-14
0.5 ml, concentrate 324M-15
1 ml, concentrate 324M-16
1 ml, predilute 324M-17
7 ml, predilute 324M-18

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 324M-14
0.5 ml, concentrate 324M-15
1 ml, concentrate 324M-16
1 ml, predilute 324M-17
7 ml, predilute 324M-18

For research use only (RUO) in the EU

DescriptionCat. No.
0.1 ml, concentrate 324M-14 (RUO)
0.5 ml, concentrate 324M-15 (RUO)
1 ml, concentrate 324M-16 (RUO)
1 ml, predilute 324M-17 (RUO)
7 ml, predilute 324M-18 (RUO)

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 324M-14 (RUO)
0.5 ml, concentrate 324M-15 (RUO)
1 ml, concentrate 324M-16 (RUO)
1 ml, predilute 324M-17 (RUO)
7 ml, predilute 324M-18 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: prostate, prostate carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:50-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(24min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

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