Myosin, Smooth Muscle (SMMS-1) Mouse Monoclonal Antibody

Myosin, Smooth Muscle
Myoepitheial cells are labeled by SMMS-1 antibody in sclerosing adenosis of breast.

Myosin, Smooth Muscle (SMMS-1) Mouse Monoclonal Antibody

Specialties: Breast/Gynecological Pathology

Updated: 2017-05-24 08:46:09

Smooth Muscle Myosin, heavy chain (SMMS-1) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMMS-1 is also a myoepithelium-associated protein. Anti-SMMS-1 is a mouse monoclonal antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.1-4

  1. Werling RW, et al. Am J Surg Pathol. 2003; 27:82-90.
  2. Agoff SN, et al. Appl Immunohistochem Mol Morphol. 2001; 9:164-9.
  3. Popnikolov NK, et al. Am J Clin Pathol. 2003; 120:161-7.
  4. Lazard D, et al. Proc Natl Acad Sci USA. 1993; 90:999-1003.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate298M-14
0.5 mL concentrate298M-15
1 mL concentrate298M-16
1 mL predilute298M-17
7 mL predilute298M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate298M-14
0.5 mL concentrate298M-15
1 mL concentrate298M-16
1 mL predilute298M-17
7 mL predilute298M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate298M-14
0.5 mL concentrate298M-15
1 mL concentrate298M-16
1 mL predilute298M-17
7 mL predilute298M-18

For research use only (RUO) in Japan

0.1 mL concentrate298M-14-RUO
0.5 mL concentrate298M-15-RUO
1 mL concentrate298M-16-RUO
1 mL predilute298M-17-RUO
7 mL predilute298M-18-RUO

 

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