Fascin (55k-2) Mouse Monoclonal Antibody

Fascin
Fascin (55k-2) on lymph node.

Fascin (55k-2) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

Fascin is a 55-kd actin bundling protein involved in cell migration. Fascin is up-regulated in many human carcinomas and numerous studies have correlated Fascin over-expression with increased metastatic potential.1-2 Fascin is highly sensitive for staining Reed-Sternberg cells making it an excellent marker for classic Hodgkin’s lymphoma.3

  1. Hashimoto Y, et al. Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker? Int J Biochem Cell Biol. 2005; 37:1787-804.
  2. Tan VY, et al. Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis. BMC Med. 2013; 11:52.
  3. Pinkus GS, et al. Fascin, a sensitive new marker for Reed-Sternberg cells of hodgkin's disease. Evidence for a dendritic or B cell derivation? Am J Pathol. 1997; 150:543-62.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: Hodgkin's lymphoma
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate252M-14
0.5 mL concentrate252M-15
1 mL concentrate252M-16
1 mL predilute252M-17
7 mL predilute252M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate252M-14
0.5 mL concentrate252M-15
1 mL concentrate252M-16
1 mL predilute252M-17
7 mL predilute252M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate252M-14
0.5 mL concentrate252M-15
1 mL concentrate252M-16
1 mL predilute252M-17
7 mL predilute252M-18

For research use only (RUO) in Japan

0.1 mL concentrate252M-14-RUO
0.5 mL concentrate252M-15-RUO
1 mL concentrate252M-16-RUO
1 mL predilute252M-17-RUO
7 mL predilute252M-18-RUO

 

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