CD30 (Ber-H2) Mouse Monoclonal Antibody

CD30
CD30 (Ber-H2) on lymph node, ALCL.

CD30 (Ber-H2) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2018-01-31 14:56:06

Anti-CD30 detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders,1-3 and in embryonal carcinomas.4 Occasionally diffuse large B-cell lymphoma stains with this antibody.3 This antibody also stains plasma cells in paraffin-embedded tissue as well as reactive immunoblasts. The staining pattern of anti-CD30 in lymphoma and embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only.4

  1. Schwarting R, et al. BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed at a formol-resistant epitope. Blood. 1989; 74:1678-89.
  2. George DH, et al. Primary anaplastic large cell lymphoma of the central nervous system: prognostic effect of ALK-1 expression. Am J Surg Pathol. 2003; 27:487-93.
  3. Hedvat CV, et al. Application of tissue microarray technology to the study of non-Hodgkin's and Hodgkin's Lymphoma. Hum Pathol. 2002; 33:968-74.
  4. Dabbs DJ. Diagnostic Immunohistochemistry Theranostic and Genomic Applications. 4th Edition Saunders Elsevier. 2014; p702.

Specifications


  • Reactivity: paraffin
  • Control: Classic Hodgkin Lymphoma (Membranous); Lymphoma (Membranous)
  • Dilution Range: 1:50-1:200 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate130M-94
0.5 mL concentrate130M-95
1.0 mL concentrate130M-96
1.0 mL predilute ready-to-use130M-97
7.0 mL predilute ready-to-use130M-98

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate130M-94
0.5 mL concentrate130M-95
1.0 mL concentrate130M-96
1.0 mL predilute ready-to-use130M-97
7.0 mL predilute ready-to-use130M-98

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate130M-94
0.5 mL concentrate130M-95
1.0 mL concentrate130M-96
1.0 mL predilute ready-to-use130M-97
7.0 mL predilute ready-to-use130M-98

For research use only (RUO) in Japan

0.1 mL concentrate (RUO)130M-94-RUO
0.5 mL concentrate (RUO)130M-95-RUO
1.0 mL concentrate (RUO)130M-96-RUO
1.0 mL predilute ready-to-use (RUO)130M-97-RUO
7.0 mL predilute ready-to-use (RUO)130M-98-RUO

 

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