Synaptophysin (EP158) Rabbit Monoclonal Antibody

Synaptophysin
Synaptophysin (EP158) on neuroendocrine carcinoma (NECA).

Synaptophysin (EP158) Rabbit Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Anti-synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.1-9

  1. Navone F, et al. J Cell Biol. 1986; 103:2511-27.
  2. Wiedenmann B, et al. Cell. 1985; 41:1017-28.
  3. Kayser K, et al. Pathol Res Pract. 1988; 183:412-7.
  4. Son EI, et al. Pathol Int. 2003; 53:67-73.
  5. Conner MG, et al. Ann Diagn Pathol. 2002; 6:345-8.
  6. Lyda MH, et al. Hum Pathol. 2000; 31:980-7.
  7. Skacel M, et al. Appl Immunohistochem Mol Morphol. 2000; 8:302-9.
  8. Morrison CD, et al. Semin Diagn Pathol. 2000; 17:204-15.
  9. Kamisawa T, et al. Pathol Res Pract. 1996; 192:901-8.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: pancreatic islet cells
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate336R-14
0.5 mL concentrate336R-15
1 mL concentrate336R-16
1 mL predilute336R-17
7 mL predilute336R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate336R-14
0.5 mL concentrate336R-15
1 mL concentrate336R-16
1 mL predilute336R-17
7 mL predilute336R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate336R-14
0.5 mL concentrate336R-15
1 mL concentrate336R-16
1 mL predilute336R-17
7 mL predilute336R-18

For research use only (RUO) in Japan

0.1 mL concentrate336R-14-RUO
0.5 mL concentrate336R-15-RUO
1 mL concentrate336R-16-RUO
1 mL predilute336R-17-RUO
7 mL predilute336R-18-RUO

 

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