Neurofilament (EP79) Rabbit Monoclonal Antibody

Neurofilament
Neurofilament (EP79) on glioblastoma.

Neurofilament (EP79) Rabbit Monoclonal Antibody

Specialties: Neuropathology

Updated: 2017-05-24 08:46:09

Immunolabelling of neurofilaments (NF) is employed for study of nerve distribution of normal and abnormal tissues, and neuronal differentiation of neoplasms. NF are found in neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, neuroblastomas, and retinoblastomas. Neurofilaments are also present in paragangliomas, as well as, adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and lung small cell carcinoma also express neurofilament.1-5

  1. Leong AS-Y, et al. Manual of Diagnostic antibodies for Immnunohistochemistry. London: Greenwich Medical Media Ltd. 1999. Print. P. 162-168.
  2. Miettinen M, et al. Varying expression of cytokeratin and neurofilaments in neuroendocrine tumors of human gastrointestinal tract. Lab Invest. 1985; 52:429-36.
  3. van Muijen GN, et al. Cytokeratin and neurofilament in lung carcinomas. Am J Pathol. 1984; 116:363-9.
  4. Trojanowski JQ, et al. Expression of neurofilament antigens by normal and neoplastic human adrenal chromaffin cells. N Engl J Med. 1985; 313:101-4.
  5. Morrison CD, et al. Immunohistochemistry in the diagnosis of neoplasms of the central nervous system. Semin Diagn Pathol. 2000; 17:204-15.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: brain
  • Dilution Range: 1:100-1:500*

Package Inserts


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Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate302R-14
0.5 mL concentrate302R-15
1 mL concentrate302R-16
1 mL predilute302R-17
7 mL predilute302R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate302R-14
0.5 mL concentrate302R-15
1 mL concentrate302R-16
1 mL predilute302R-17
7 mL predilute302R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate302R-14
0.5 mL concentrate302R-15
1 mL concentrate302R-16
1 mL predilute302R-17
7 mL predilute302R-18

For research use only (RUO) in Japan

0.1 mL concentrate302R-14-RUO
0.5 mL concentrate302R-15-RUO
1 mL concentrate302R-16-RUO
1 mL predilute302R-17-RUO
7 mL predilute302R-18-RUO

 

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