Alpha-Fetoprotein (EP209) Rabbit Monoclonal Antibody
Specialties: Anatomic Pathology
Alpha-fetoprotein (AFP) is a fetal tumor-associated polypeptide of the albuminoid gene family that binds and transports molecules in addition to many other proposed functions.1 This secretory protein is synthesized primarily in the fetal liver whereas expression is repressed in adult liver.2 Anti-AFP has been immunohistochemically demonstrated in hepatocellular carcinoma (HCC) and shows no immunoreactivity in normal liver.3
- Mizejewski GJ. Alpha-fetoprotein structure and function: relevance to isoforms, epitopes, and conformational variants. Exp Biol Med. 2001; 226: 377-408.
- Lazarevich NL. Molecular mechanisms of alpha-fetoprotein gene expression. Biochemistry (Mosc). 2000; 65:117-33.
- Yusof YA, et al. Immunohistochemical expression of pi class glutathione S-transferase and alpha-fetoprotein in hepatocellular carcinoma and chronic liver disease. Anal Quant Cytol Histol. 2003; 25:332-8.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: fetal liver
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 3.0 (CMC20331030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 203R-14 |
| 0.5 mL concentrate | 203R-15 |
| 1 mL concentrate | 203R-16 |
| 1 mL predilute | 203R-17 |
| 7 mL predilute | 203R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 203R-14 |
| 0.5 mL concentrate | 203R-15 |
| 1 mL concentrate | 203R-16 |
| 1 mL predilute | 203R-17 |
| 7 mL predilute | 203R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 203R-14 |
| 0.5 mL concentrate | 203R-15 |
| 1 mL concentrate | 203R-16 |
| 1 mL predilute | 203R-17 |
| 7 mL predilute | 203R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 203R-14-RUO |
| 0.5 mL concentrate | 203R-15-RUO |
| 1 mL concentrate | 203R-16-RUO |
| 1 mL predilute | 203R-17-RUO |
| 7 mL predilute | 203R-18-RUO |
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