SALL4 (6E3) Mouse Monoclonal Antibody

SALL4
Anti-SALL4 labels the nuclei of seminoma tumor cells.

SALL4 (6E3) Mouse Monoclonal Antibody

Specialties: Genitourinary (GU) Pathology

Updated: 2017-05-24 08:46:09

Sal-like protein 4 (SALL4) is a zinc-finger transcription factor1 that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities.2 SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas.1 SALL4 expression is also seen in the spermatogonia of normal testis.

  1. Miettinen M, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014; 38:410-20.
  2. Yang J, et al. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. PNAS. 2008; 105:19756-61.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: seminoma, dysgerminoma
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate385M-14
0.5 mL concentrate385M-15
1 mL concentrate385M-16
1 mL predilute385M-17
7 mL predilute385M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate385M-14
0.5 mL concentrate385M-15
1 mL concentrate385M-16
1 mL predilute385M-17
7 mL predilute385M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate385M-14
0.5 mL concentrate385M-15
1 mL concentrate385M-16
1 mL predilute385M-17
7 mL predilute385M-18

For research use only (RUO) in Japan

0.1 mL concentrate385M-14-RUO
0.5 mL concentrate385M-15-RUO
1 mL concentrate385M-16-RUO
1 mL predilute385M-17-RUO
7 mL predilute385M-18-RUO

 

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