Oct-4 (MRQ-10) Mouse Monoclonal Antibody

Oct-4
Oct-4 antibody labels seminoma cells in a nuclear pattern.

Oct-4 (MRQ-10) Mouse Monoclonal Antibody

Specialties: Genitourinary (GU) Pathology

Updated: 2017-05-24 08:46:09

Oct-4 is a transcription factor that functions in the regulation and maintenance of pluripotency in embryonic stem and primordial germ cells.1 Oct-4 immunoreactivity has been demonstrated in gonadal and extra-gonadal seminomas, dysgerminomas and embryonal carcinomas.1,2 In addition, the immunohistochemical detection of Oct-4 assists in the evaluation of intratubular germ cell neoplasia (IGCN).1

  1. Cheng L, et al. OCT4: biological functions and clinical applications as a marker of germ cell neoplasia. J Pathol. 2007; 211:1-9.
  2. Weissferdt A, et al. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015; 46:376-83.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: seminoma
  • Dilution Range: 1:50-1:200*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate309M-14
0.5 mL concentrate309M-15
1 mL concentrate309M-16
1 mL predilute309M-17
7 mL predilute309M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate309M-14
0.5 mL concentrate309M-15
1 mL concentrate309M-16
1 mL predilute309M-17
7 mL predilute309M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate309M-14
0.5 mL concentrate309M-15
1 mL concentrate309M-16
1 mL predilute309M-17
7 mL predilute309M-18

For research use only (RUO) in Japan

0.1 mL concentrate309M-14-RUO
0.5 mL concentrate309M-15-RUO
1 mL concentrate309M-16-RUO
1 mL predilute309M-17-RUO
7 mL predilute309M-18-RUO

 

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