MUC4 (8G7) Mouse Monoclonal Antibody

MUC4
Infiltrating adenocarcinoma of stomach surrounding nerve is labelled by anti-MUC4.

MUC4 (8G7) Mouse Monoclonal Antibody

Specialties: Soft Tissue Pathology

Updated: 2017-05-24 08:46:09

MUC4 (mucin 4) is a large membrane-anchored glycoprotein of the mucin family that is expressed by epithelial cells in various normal tissues including lung, bronchus, stomach, colon, and cervix.1 MUC4 is generally not detected in normal pancreas, but is expressed in the vast majority of pancreatic neoplasms, such as pancreatic ductal adenocarcinoma.2  Additionally, expression in various carcinomas has been reported, including gastric adenocarcinoma, colon adenocarcinoma, and lung adenocarcinoma.3

  1. Moniaux N, et al. Generation and characterization of anti-MUC4 monoclonal antibodies reactive with normal and cancer cells in humans. J Histochem Cytochem. 2004; 52:253-61.
  2. Moniaux N, et al. Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy. Br J Cancer. 2004;91:1633-8.
  3. Llinares K, et al. Diagnostic value of MUC4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma. Mod Pathol. 2004;17:150-7.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: pancreatic ductal adenocarcinoma, colon, colorectal adenocarcinoma
  • Dilution Range: 1:10-1:50*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate406M-14
0.5 mL concentrate406M-15
1 mL concentrate406M-16
1 mL predilute406M-17
7 mL predilute406M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate406M-14
0.5 mL concentrate406M-15
1 mL concentrate406M-16
1 mL predilute406M-17
7 mL predilute406M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate406M-14
0.5 mL concentrate406M-15
1 mL concentrate406M-16
1 mL predilute406M-17
7 mL predilute406M-18

For research use only (RUO) in Japan

0.1 mL concentrate406M-14-RUO
0.5 mL concentrate406M-15-RUO
1 mL concentrate406M-16-RUO
1 mL predilute406M-17-RUO
7 mL predilute406M-18-RUO

 

To request information on this product in additional countries, please click the button below.

Request More Information