c-Myc (EP121) Rabbit Monoclonal Antibody

c-Myc
Burkitt lymphoma is positive for c-Myc.

c-Myc (EP121) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

The oncogenic transcription factor, c-MYC, has a crucial role in growth control, differentiation, cellular metabolism and apoptosis and is associated with variety of tumors.1 c-Myc antibody stains this protein in tissues from colorectal adenocarcinoma,2 breast invasive ductal carcinoma,3 prostate adenocarcinoma,4 Burkitt lymphoma, and diffused large B-cell lymphoma.5

  1. Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol. 1999; 19:1-11.
  2. Toon CW, et al. Immunohistochemistry for myc predicts survival in colorectal cancer. PLoS One. 2014; 9:e87456.
  3. Naidu R, et al. Protein expression and molecular analysis of c-myc gene in primary breast carcinomas using immunohistochemistry and differential polymerase chain reaction. Int J Mol Med. 2002; 9:189-96.
  4. Yang G, et al. Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression. Cancer. 2005; 103:1186-94.
  5. Bellan C, et al. Burkitt lymphoma versus diffuse large B-cell lymphoma: a practical approach. Hematol Oncol. 2010; 28:53-6.

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: Burkitt lymphoma, prostate carcinoma
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate395R-14
0.5 mL concentrate395R-15
1 mL concentrate395R-16
1 mL predilute395R-17
7 mL predilute395R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate395R-14
0.5 mL concentrate395R-15
1 mL concentrate395R-16
1 mL predilute395R-17
7 mL predilute395R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate395R-14
0.5 mL concentrate395R-15
1 mL concentrate395R-16
1 mL predilute395R-17
7 mL predilute395R-18

For research use only (RUO) in Japan

0.1 mL concentrate395R-14-RUO
0.5 mL concentrate395R-15-RUO
1 mL concentrate395R-16-RUO
1 mL predilute395R-17-RUO
7 mL predilute395R-18-RUO

 

To request information on this product in additional countries, please click the button below.

Literature

Request More Information