Ki-67 (SP6) Rabbit Monoclonal Antibody

Ki-67
Ki-67 (SP6) on tonsil.

Ki-67 (SP6) Rabbit Monoclonal Antibody

Specialties: Anatomic Pathology Breast/Gynecological Pathology

Updated: 2018-01-31 15:18:30

The Ki-67 antigen is a nuclear, non-histone protein that is present in proliferating cells. In general, Ki-67 is a good marker of proliferating cell populations. Anti-Ki-67 labeling index has been shown to be a good marker to grade neoplasms including:  colon carcinoma, breast carcinoma, and  lymphoma.1-5

  1. McKeever P, et al. MIB-1 proliferation index predicts survival among patients with grade II astrocytoma. J Neuropathol Exp Neurol. 1998; 57:931-6.
  2. Coons SW, et al. The prognostic significance of Ki-67 labeling indices for oligodendrogliomas. Neurosurgery. 1997; 41:878-84.
  3. Allegra CJ, et al. Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol. 2003; 21:241-50.
  4. Pathmanathan N, et al. Ki-67 and proliferation in breast cancer. J Clin Pathol. 2013; 66:512-6.
  5. Swerdlow SH, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th edition. 2008; p220.

Specifications


  • Reactivity: paraffin
  • Control: Tonsil (Nuclear)
  • Dilution Range: 1:100-1:500 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

25.0 mL predilute ready-to-use275R-10
0.1 mL concentrate275R-14
0.5 mL concentrate275R-15
1.0 mL concentrate275R-16
1.0 mL predilute ready-to-use275R-17
7.0 mL predilute ready-to-use275R-18

For in vitro diagnostic (IVD) use in Canada

25.0 mL predilute ready-to-use275R-10
0.1 mL concentrate275R-14
0.5 mL concentrate275R-15
1.0 mL concentrate275R-16
1.0 mL predilute ready-to-use275R-17
7.0 mL predilute ready-to-use275R-18

For in vitro diagnostic (IVD) use in Europe

25.0 mL predilute ready-to-use275R-10
0.1 mL concentrate275R-14
0.5 mL concentrate275R-15
1.0 mL concentrate275R-16
1.0 mL predilute ready-to-use275R-17
7.0 mL predilute ready-to-use275R-18

For research use only (RUO) in Japan

25.0 mL predilute ready-to-use (RUO)275R-10-RUO
0.1 mL concentrate (RUO)275R-14-RUO
0.5 mL concentrate (RUO)275R-15-RUO
1.0 mL concentrate (RUO)275R-16-RUO
1.0 mL predilute ready-to-use (RUO)275R-17-RUO
7.0 mL predilute ready-to-use (RUO)275R-18-RUO

 

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