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GATA3 (L50-823)

Mouse Monoclonal


GATA binding protein 3 or GATA3, is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types.1-4 The human GATA3 gene has been mapped to chromosome 10p15.3  GATA3 expression is primarily seen in breast carcinoma and urothelial carcinoma.1-2  Anti-GATA3 can also be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.

Specialties: Anatomic Pathology Breast/Gynecological Pathology Genitourinary (GU) Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma, urothelial carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/32min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/5

Package Inserts


IFU SDS

References


  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-680.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.
  3. Joulin V, et al. EMBO J. 1991; 10: 1809-16.
  4. Labastie M, et al. Genomics; 21:1-6.

Last updated: 2017-05-24 08:46:09

GATA3
Mouse monoclonal anti-GATA3 demonstrates a strong diffuse and nuclear reaction in neoplastic cells of invasive ductal carcinoma of the breast.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma, urothelial carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/32min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/5

References


  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-680.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.
  3. Joulin V, et al. EMBO J. 1991; 10: 1809-16.
  4. Labastie M, et al. Genomics; 21:1-6.

Package Inserts

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Ordering Information

For in vitro diagnostic (IVD) use in USA

25 mL predilute 390M-10
0.1 mL concentrate 390M-14
0.5 mL concentrate 390M-15
1 mL concentrate 390M-16
1 mL predilute 390M-17
7 mL predilute 390M-18

For in vitro diagnostic (IVD) use in Canada

25 mL predilute 390M-10
0.1 mL concentrate 390M-14
0.5 mL concentrate 390M-15
1 mL concentrate 390M-16
1 mL predilute 390M-17
7 mL predilute 390M-18

For in vitro diagnostic (IVD) use in Europe

25 mL predilute 390M-10
0.1 mL concentrate 390M-14
0.5 mL concentrate 390M-15
1 mL concentrate 390M-16
1 mL predilute 390M-17
7 mL predilute 390M-18

For research use only (RUO) in Japan

25 mL predilute 390M-10-RUO
0.1 mL concentrate 390M-14-RUO
0.5 mL concentrate 390M-15-RUO
1 mL concentrate 390M-16-RUO
1 mL predilute 390M-17-RUO
7 mL predilute 390M-18-RUO

 

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma, urothelial carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/32min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/5

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References


  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-680.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.
  3. Joulin V, et al. EMBO J. 1991; 10: 1809-16.
  4. Labastie M, et al. Genomics; 21:1-6.
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