Cell Marque Portfolio

GATA3 (L50-823)

Mouse Monoclonal


GATA binding protein 3 or GATA3, is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types.1-4 The human GATA3 gene has been mapped to chromosome 10p15.3  GATA3 expression is primarily seen in breast carcinoma and urothelial carcinoma.1-2  Anti-GATA3 can also be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.

Specialties: Anatomic Pathology Breast/Gynecological Pathology Genitourinary (GU) Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma, urothelial carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/32min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/5

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*Note: IFUs with the prefix RUO or ASR are only available for download in English.


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References


  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-680.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.
  3. Joulin V, et al. EMBO J. 1991; 10: 1809-16.
  4. Labastie M, et al. Genomics; 21:1-6.

Last updated: 2017-03-02 12:03:43

GATA3
Mouse monoclonal anti-GATA3 demonstrates a strong diffuse and nuclear reaction in neoplastic cells of invasive ductal carcinoma of the breast.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma, urothelial carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/32min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/5

References


  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-680.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.
  3. Joulin V, et al. EMBO J. 1991; 10: 1809-16.
  4. Labastie M, et al. Genomics; 21:1-6.

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 390M-14
0.5 ml, concentrate 390M-15
1 ml, concentrate 390M-16
1 ml, predilute 390M-17
7 ml, predilute 390M-18
25 ml, predilute 390M-10

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 390M-14
0.5 ml, concentrate 390M-15
1 ml, concentrate 390M-16
1 ml, predilute 390M-17
7 ml, predilute 390M-18
25 ml, predilute 390M-10

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 390M-14
0.5 ml, concentrate 390M-15
1 ml, concentrate 390M-16
1 ml, predilute 390M-17
7 ml, predilute 390M-18
25 ml, predilute 390M-10

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 390M-14 (RUO)
0.5 ml, concentrate 390M-15 (RUO)
1 ml, concentrate 390M-16 (RUO)
1 ml, predilute 390M-17 (RUO)
7 ml, predilute 390M-18 (RUO)
25 ml, predilute 390M-10 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma, urothelial carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/32min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C
  • Leica Bond
    Protocol F: ER1/5

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

References


  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-680.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.
  3. Joulin V, et al. EMBO J. 1991; 10: 1809-16.
  4. Labastie M, et al. Genomics; 21:1-6.
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