Parathyroid Hormone (PTH) (MRQ-31) Mouse Monoclonal Antibody
Specialties: Head/Neck Pathology
The parathyroid glands function within the endocrine system to promote blood calcium homeostasis through controlled release of parathyroid hormone (PTH). This process involves the synthesis and secretion of PTH by activated parathyroid chief cells during conditions of hypocalcemia.1 With the anatomical proximity to the thyroid and capacity of associated neoplasms of the parathyroid to mimic thyroid tumors, challenges can arise in distinguishing between these types of abnormalities. In cases where there is uncertainty about a tumor being of parathyroid origin, immunohistochemical evaluation using anti-PTH can be of value.2,3
- Abate EG, et al. Review of Hypoparathyroidism. Front Endocrinol (Lausanne). 2017; 7:172.
- Chang TC, et al. Immunoperoxidase staining in the differential diagnosis of parathyroid from thyroid origin in fine needle aspirates of suspected parathyroid lesions. Acta Cytol. 1998; 42:619-624.
- Duan K, et al. Parathyroid Carcinoma: Diagnosis and Clinical Implications. Turk Patoloji Derg. 2015; 31 Suppl 1:80-97.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: parathyroid tissue
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 5.0 (CMC31022050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 310M-24 |
| 0.5 mL concentrate | 310M-25 |
| 1 mL concentrate | 310M-26 |
| 1 mL predilute | 310M-27 |
| 7 mL predilute | 310M-28 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 310M-24 |
| 0.5 mL concentrate | 310M-25 |
| 1 mL concentrate | 310M-26 |
| 1 mL predilute | 310M-27 |
| 7 mL predilute | 310M-28 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 310M-24 |
| 0.5 mL concentrate | 310M-25 |
| 1 mL concentrate | 310M-26 |
| 1 mL predilute | 310M-27 |
| 7 mL predilute | 310M-28 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 310M-24-RUO |
| 0.5 mL concentrate | 310M-25-RUO |
| 1 mL concentrate | 310M-26-RUO |
| 1 mL predilute | 310M-27-RUO |
| 7 mL predilute | 310M-28-RUO |
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