Parathyroid Hormone (PTH) (MRQ-31) Mouse Monoclonal Antibody

Parathyroid Hormone (PTH)
Anti-PTH labels hyperplastic parathyroid glands in a cytoplasmic pattern.

Parathyroid Hormone (PTH) (MRQ-31) Mouse Monoclonal Antibody

Specialties: Head/Neck Pathology

Updated: 2017-06-02 08:33:36

The parathyroid glands function within the endocrine system to promote blood calcium homeostasis through controlled release of parathyroid hormone (PTH).  This process involves the synthesis and secretion of PTH by activated parathyroid chief cells during conditions of hypocalcemia.1 With the anatomical proximity to the thyroid and capacity of associated neoplasms of the parathyroid to mimic thyroid tumors, challenges can arise in distinguishing between these types of abnormalities. In cases where there is uncertainty about a tumor being of parathyroid origin, immunohistochemical evaluation using anti-PTH can be of value.2,3

  1. Abate EG, et al. Review of Hypoparathyroidism. Front Endocrinol (Lausanne). 2017; 7:172.
  2. Chang TC, et al. Immunoperoxidase staining in the differential diagnosis of parathyroid from thyroid origin in fine needle aspirates of suspected parathyroid lesions. Acta Cytol. 1998; 42:619-624.
  3. Duan K, et al. Parathyroid Carcinoma: Diagnosis and Clinical Implications. Turk Patoloji Derg. 2015; 31 Suppl 1:80-97.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: parathyroid tissue
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate310M-24
0.5 mL concentrate310M-25
1 mL concentrate310M-26
1 mL predilute310M-27
7 mL predilute310M-28

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate310M-24
0.5 mL concentrate310M-25
1 mL concentrate310M-26
1 mL predilute310M-27
7 mL predilute310M-28

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate310M-24
0.5 mL concentrate310M-25
1 mL concentrate310M-26
1 mL predilute310M-27
7 mL predilute310M-28

For research use only (RUO) in Japan

0.1 mL concentrate310M-24-RUO
0.5 mL concentrate310M-25-RUO
1 mL concentrate310M-26-RUO
1 mL predilute310M-27-RUO
7 mL predilute310M-28-RUO

 

To request information on this product in additional countries, please click the button below.

Request More Information