Calcitonin (SP17) Rabbit Monoclonal Antibody

Calcitonin
Rabbit monoclonal calcitonin antibody labels C-cells in this normal-appearing thyroid.

Calcitonin (SP17) Rabbit Monoclonal Antibody

Specialties: Cytopathology Head/Neck Pathology

Updated: 2018-01-11 08:35:53

Immunohistochemical staining with anti-calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities.1-5

  1. Copp DH, et al. Evidence for calcitonin--a new hormone from the parathyroid that lowers blood calcium. Endocrinology. 1962; 70:638-49.
  2. Kameda Y, et al. Development and cytodifferentiation of C cell complexes in dog fetal thyroids. An immunohistochemical study using anti-calcitonin, anti-C-thyroglobulin and anti-19S thyroglobulin antisera. Cell Tissue Res. 1980; 206:403-15.
  3. Coombes RC, et al. Plasma-immunoreactive-calcitonin in patients with non-thyroid tumours. Lancet. 1974; 1:1080-3.
  4. Dayal Y, et al. Immunocytochemical localization of calcitonin-producing cells in a strumal carcinoid with amyloid stroma. Cancer. 1979; 43:1331-8.
  5. DeLellis RA, et al. Calcitonin and carcinoembryonic antigen as tumor markers in medullary thyroid carcinoma. Am J Clin Pathol. 1978; 70:587-94.

Specifications


  • Reactivity: paraffin
  • Control: Thyroid (Cytoplasmic); Thyroid Medullary Carcinoma (Cytoplasmic)
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate229R-14
0.5 mL concentrate229R-15
1.0 mL concentrate229R-16
1.0 mL predilute ready-to-use229R-17
7.0 mL predilute ready-to-use229R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate229R-14
0.5 mL concentrate229R-15
1.0 mL concentrate229R-16
1.0 mL predilute ready-to-use229R-17
7.0 mL predilute ready-to-use229R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate229R-14
0.5 mL concentrate229R-15
1.0 mL concentrate229R-16
1.0 mL predilute ready-to-use229R-17
7.0 mL predilute ready-to-use229R-18

For research use only (RUO) in Japan

0.1 mL concentrate (RUO)229R-14-RUO
0.5 mL concentrate (RUO)229R-15-RUO
1.0 mL concentrate (RUO)229R-16-RUO
1.0 mL predilute ready-to-use (RUO)229R-17-RUO
7.0 mL predilute ready-to-use (RUO)229R-18-RUO

 

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