MUC6 (MRQ-20) Mouse Monoclonal Antibody

MUC6
MUC6 antibody labels gastric mucosa cytoplasm in the deep crypts.

MUC6 (MRQ-20) Mouse Monoclonal Antibody

Specialties: Gastrointestinal (GI) Pathology

Updated: 2017-05-24 08:46:09

MUC6 is a secretory mucin that is part of a family of at least 14 high molecular weight glycoproteins made by many epithelial tissues.1 MUC6 is preferentially expressed in non-neoplastic gastric tissue, specifically in the pyloric glands.1, 2 During neoplastic transformation, mucin expression may be altered within these tissues leading to particular patterns of expression.2-3

  1. Rakha EA, et al. Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer. Mod Pathol. 2005; 18:1295-304.
  2. Do SI. et al. Associations between the Expression of Mucins (MUC1, MUC2, MUC5AC, and MUC6) and Clinicopathologic Parameters of Human Breast Ductal Carcinomas. J of Breast Cancer. 2013; 16:152-8.
  3. Mino-Kenudson M, et al. Mucin expression in Betge J. et al. MUC1, MUC2, MUC5AC and MUC6 in colorectal cancer: expression profiles and clinical significance. Virchows Arch. 2016; 469:255-65.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: stomach
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate293M-94
0.5 mL concentrate293M-95
1 mL concentrate293M-96
1 mL predilute293M-97
7 mL predilute293M-98

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate293M-94
0.5 mL concentrate293M-95
1 mL concentrate293M-96
1 mL predilute293M-97
7 mL predilute293M-98

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate293M-94
0.5 mL concentrate293M-95
1 mL concentrate293M-96
1 mL predilute293M-97
7 mL predilute293M-98

For research use only (RUO) in Japan

0.1 mL concentrate293M-94-RUO
0.5 mL concentrate293M-95-RUO
1 mL concentrate293M-96-RUO
1 mL predilute293M-97-RUO
7 mL predilute293M-98-RUO

 

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